上纵隔畸胎瘤1例并文献复习

E. A. Hamdi, Rabea Salim Abd Aljabbar Sofi Ali, W. Al-Nuaimy
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引用次数: 0

摘要

畸胎瘤是一种生殖细胞肿瘤,由两层或三层胚层(外胚层、中胚层和内胚层)形成的组织组成。畸胎瘤多见于儿童和青年,通常起源于性腺和角外中线组织,如腹膜后、骶尾骨区和纵隔。纵隔畸胎瘤相对罕见,占胸腔内所有肿瘤的3%,平均每年发病率为8例,前纵隔是这些肿瘤最常见的部位,良性畸胎瘤仅占10%。我们报告一例39岁男性患者,其表现为进行性用力性呼吸困难,直喘并频繁咳嗽3年,近4个月左胸骨旁区搏动性肿块。胸部x线示上纵隔影向左上胸区突出,气管向胸部右侧偏离,初步诊断为主动脉弓动脉瘤。胸部计算机断层扫描和CT血管造影显示上纵隔肿块不均匀混浊,含液体、软组织、骨骼和钙化,侵犯右肺动脉,压迫并使气管向右偏斜。通过左开胸手术完全切除,最终病理诊断为成熟囊性畸胎瘤。本病例之所以在此提出,是因为纵隔是一个罕见的畸胎瘤的部位,而纵隔上畸胎瘤在文献回顾中报道的病例很少。
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Superior Mediastinal Teratoma- A Case Report with review of literature
"A teratoma is a germ cell tumor composed of tissue derived from two or three germ layers-ectoderm, mesoderm, and endoderm". Teratomas are mostly found in children & young adults & usually originated in gonads & extragonadal midline tissues such as retroperitoneum, sacrococcygeal region & mediastinum. Mediastinal teratomas are relatively rare representing 3% of all tumors within the chest with an average incidence of 8 cases per year and the anterior mediastinum being the most common site for these tumors, benign teratomas form only 10% of them. We are presenting a case of 39 years old male who presented with progressive exertional dyspnea, orthopnea with frequent attacks of cough for 3years and feeling of pulsatile mass in left upper parasternal area in the last 4 months. Chest x-ray showed superior mediastinal shadow projecting to left upper chest zone and deviating the trachea to the right side of chest, provisional diagnosis was aneurysm of aortic arch. Computed tomography (CT) scan of chest and CT angiography done and revealed a superior mediastinal mass of heterogeneous opacity containing fluid, soft tissue, bones and calcification encroaching the right pulmonary artery and compressing and deviating the trachea to the right. Complete surgical removal done through left thoracotomy, Final diagnosis of a mature cystic teratoma was given on histopathology. This case is being presented here because mediastinum is a rare site for teratoma and superior mediastinal teratoma was reported in only few cases from review of literature.
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15
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15 weeks
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