芦荟局部凝胶的开发与评价:治疗银屑病的新方法

Anurag Kumar, V. Pandit, T. Sharma
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引用次数: 0

摘要

本研究旨在开发和评价芦荟外用凝胶治疗银屑病的新方法。以不同浓度的芦荟为原料,设计外用凝胶配方。以环孢素为药物,以卡波波尔940、甲醇、丙二醇、对羟基苯甲酸甲酯、对羟基苯甲酸丙酯、三乙醇胺为辅料,加入适量水制备凝胶。对制备的凝胶进行了物理外观、PH、扩散能力、药物含量、膨胀指数、扩散研究、粘度、均质性、可挤压性和砂性的评估。由此推断,凝胶制剂具有良好的外观和均匀性。所制备的草药凝胶对治疗牛皮癣具有抗增殖和抗炎作用。©2019 igglobal研究与出版基金会。版权所有。引用本文如下:Kumar, A.;潘迪特,诉;芦荟局部凝胶的开发和评价:治疗牛皮癣的新方法。印度国际制药公司。科学。, 2019;9(2生理):125。DOI: http://doi.org/10.35652/IGJPS.2019.92S23。印度全球药物科学杂志(ISSN 2249 1023;CODENIGJPAI;NLM ID: 101610675)在CrossRef (DOI Enabling), UGC CARE Journal List, EMBASE(Elsevier), National Library of Medicine (NLM) Catalog, ResearchGate, Publons, CAS (ACS), Index哥白尼,Google Scholar等中索引和摘要。欲了解更多详情,请访问http://iglobaljournal.com这是由APTI赞助,印度旁遮普阿姆利则马纳瓦拉斯里赛药学院组织的“RAPSCON-2019”的特刊。以日志形式提供放松。
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Development and Evaluation of Topical Gel with Aloe vera: Novel Treatment of Psoriasis
The present studies aim that development and evaluation of topical gel with aloe Vera novel treatment for psoriasis. Topical gel formulation was designed by using Aloe Vera in varied concentration. The gel was prepared by using cyclosporine as drug with other excipients such as carbopol 940, methanol, propylene glycol, methyl paraben, propyl paraben, tri-ethanolamine and required amount of water. The prepared gel was evaluated for physical appearance, PH, spread ability, drug content, swelling index, diffusion study, viscosity, homogenicity, extrudability, and grittiness. It was inferred from that gel formulation were good in appearance and homogenicity. The prepared herbal gel is very useful for the anti proliferative and anti-inflammatory action for the treatment of psoriasis. © 2019 iGlobal Research and Publishing Foundation. All rights reserved. Cite this article as: Kumar, A.; Pandit, V.; Sharma, T. Development and Evaluation of Topical Gel with Aloe vera: Novel Treatment of Psoriasis. Indo Global J. Pharm. Sci., 2019; 9(2Suppl.): 125. DOI: http://doi.org/10.35652/IGJPS.2019.92S23 . Indo Global Journal of Pharmaceutical Sciences( ISSN 2249 1023; CODENIGJPAI; NLM ID: 101610675) indexed and abstracted in CrossRef (DOI Enabling), UGC CARE Journal List, EMBASE(Elsevier), National Library of Medicine (NLM) Catalog, ResearchGate, Publons, CAS (ACS), Index Copernicus, Google Scholar and many more. For further details, visit http://iglobaljournal.com This is a special issue as an outcome of ‘RAPSCON-2019’ sponsored by APTI and organized by Sri Sai College of Pharmacy, Manawala, Amritsar, Punjab, India. Relaxation offered in journal format.
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