{"title":"脑深部电刺激还是苍白球切开术治疗脑铁积累性神经退行性肌张力障碍?呼吁公正与平衡","authors":"Guach‑Hevia David Armando","doi":"10.36959/459/609","DOIUrl":null,"url":null,"abstract":"Neurodegeneration with brain iron accumulation (NBIA) comprises a group of rare but devastating inherited neurological diseases with unifying features of gradual cognitive and motor decline, and progressive degeneration of basal ganglia, globus pallidus, and reticular part of substantia nigra, produced by brain iron accumulation [1]. The most common disorders presented in infancy and childhood are Betapropeller Protein‐Associated Neurodegeneration, Pantothenate Kinase‐ Associated Neurodegeneration, PhosphoLipase A2‐Associated Neurodegeneration, and Mitochondrial membrane Protein‐ Associated Neurodegeneration [2].","PeriodicalId":92384,"journal":{"name":"International journal of neurodegenerative disorders","volume":"76 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Deep Brain Stimulation or Pallidotomy for Dystonia in Neurodegeneration with Brain Iron Accumulation? A Call for Justice To the Balance\",\"authors\":\"Guach‑Hevia David Armando\",\"doi\":\"10.36959/459/609\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Neurodegeneration with brain iron accumulation (NBIA) comprises a group of rare but devastating inherited neurological diseases with unifying features of gradual cognitive and motor decline, and progressive degeneration of basal ganglia, globus pallidus, and reticular part of substantia nigra, produced by brain iron accumulation [1]. The most common disorders presented in infancy and childhood are Betapropeller Protein‐Associated Neurodegeneration, Pantothenate Kinase‐ Associated Neurodegeneration, PhosphoLipase A2‐Associated Neurodegeneration, and Mitochondrial membrane Protein‐ Associated Neurodegeneration [2].\",\"PeriodicalId\":92384,\"journal\":{\"name\":\"International journal of neurodegenerative disorders\",\"volume\":\"76 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International journal of neurodegenerative disorders\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.36959/459/609\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International journal of neurodegenerative disorders","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36959/459/609","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
脑铁积累性神经变性(Neurodegeneration with brain iron accumulation, NBIA)是一组罕见但具有破坏性的遗传性神经系统疾病,其共同特征是脑铁积累导致认知和运动能力逐渐下降,基底节、苍白球和黑质网状部分进行性变性[1]。婴儿期和儿童期最常见的疾病是β -螺旋桨蛋白相关神经变性、泛酸激酶相关神经变性、磷脂酶A2相关神经变性和线粒体膜蛋白相关神经变性[2]。
Deep Brain Stimulation or Pallidotomy for Dystonia in Neurodegeneration with Brain Iron Accumulation? A Call for Justice To the Balance
Neurodegeneration with brain iron accumulation (NBIA) comprises a group of rare but devastating inherited neurological diseases with unifying features of gradual cognitive and motor decline, and progressive degeneration of basal ganglia, globus pallidus, and reticular part of substantia nigra, produced by brain iron accumulation [1]. The most common disorders presented in infancy and childhood are Betapropeller Protein‐Associated Neurodegeneration, Pantothenate Kinase‐ Associated Neurodegeneration, PhosphoLipase A2‐Associated Neurodegeneration, and Mitochondrial membrane Protein‐ Associated Neurodegeneration [2].