精神外科:从前额叶切除术到深部脑刺激的历史

A. Yousaf, K. Singh, Victoria Tavernor, A. Baldwin
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摘要

神经外科治疗精神疾病具有悠久而有争议的历史。这篇文章探讨了“精神外科的范围”,描述了老式的和有争议的前额叶白质切除术是如何逐渐演变成现代的,主流科学的深部脑刺激(DBS)。我们关注的是今天作为一种治疗干预手段的精神外科的兴起、衰落和可能的重新出现。我们回顾了历史上对前额叶白质切除术的滥用,这引起了公众和专业人士的严厉批评,直到现代DBS的发展——为患有严重的、难以治疗的强迫症(OCD)、癫痫和运动障碍症状的患者进行治疗。我们希望这篇文章将为理解现有治疗方案的可用性和潜在的未来机会提供一个基础,同时挑战任何公众/专业人士对精神外科的先入之见,这些先入之见可能会间接阻碍患者的护理。此外,我们还进行了一项以WordCloud格式显示的定性调查,捕捉了为西北行政区NHS医疗保健基金会信托工作的38名精神卫生专业人员对“精神外科”、“前额叶切除术”和“脑起脑展”的看法,这可能很好地反映了更广泛的公众舆论。总之,这篇文章提供了一个简短的,但全面的概述有争议的历史的精神外科,目前的实践,和未来的趋势神经外科精神疾病。
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Psychosurgery : A history from Prefrontal Lobotomy to Deep Brain Stimulation
Neurosurgical treatment for psychiatric disorders features a long and controversial history. This article explores a ‘spectrum of psychosurgery,’ describing how old-fashioned and controversial prefrontal lobotomy gradually evolved into modern day, mainstream scientific deep brain stimulation (DBS). We focus on the rise, fall and possible re-emergence of psychosurgery as a therapeutic intervention today.We journey through historic indiscriminate use of prefrontal lobotomy, which evoked stern criticism from both public and professionals, through to the development of modern day DBS - performed for patients suffering from severe, treatment resistant symptoms of obsessive-compulsive disorder (OCD), epilepsy and movement disorders.We hope this article will provide a basis for understanding the availability of existing treatment options and potential future opportunities, whilst simultaneously challenging any public/professional preconceptions of psychosurgery, which may indirectly be obstructing patient care.Additionally, we carried out a qualitative survey displayed in WordCloud Format, capturing the intellection of 38 mental health professionals working for North West Boroughs NHS Healthcare Foundation Trust, on ‘psychosurgery,’ ‘prefrontal lobotomy’ and ‘DBS’, which may well reflect wider public opinion.In summary, the article provides a brief, yet comprehensive overview of the controversial history of psychosurgery, present-day practice, and future trends of neurosurgery for psychiatric disorders.
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