一例罕见的肺动静脉畸形-诊断困境

U. Desai, Neenu N, K. Utpat, Ammar Modi, Kishor L. Rajpal, D. Shetty, R. Bharmal
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引用次数: 0

摘要

肺动静脉畸形(Pulmonary arteriovenous malformations, PAVM)是一种罕见的肺血管系统异常,可能是偶然发现的,也可能是由右至左分流引起的。PAVM可引起各种系统性影响,包括中枢神经系统并发症,如中风,由矛盾栓子引起的脑脓肿,这主要见于先前未诊断的PAVM,这表明早期诊断和及时干预PAVM的重要性。计算机断层肺血管造影(CTPA)是诊断PAVM的首选方法。我们在此报告一个独特的复杂多发性PAVM病例,其表现为难治性低氧血症,这是一位在我们中心诊断的中年患者,最初根据胸片和高分辨率计算机断层扫描(HRCT)的胸部表现和症状评估为恶性肿瘤,后来在CTPA被诊断为复杂的PAVM后,在肺血管堵塞后显示临床放射学改善。本病例的临床表现、诊断和治疗方法及鉴别诊断值得讨论,并与相似的临床放射学模式及高龄PAVM的特殊性相比较。
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A Rare Case of Pulmonary Arteriovenous Malformation - A Diagnostic Dilemma
Pulmonary arteriovenous malformations (PAVM) are rare anomalies of pulmonary vascular system which may be incidentally detected or can have manifestations resulting from right to left shunt. PAVM can cause various systemic implications including central nervous system complications like stroke, brain abscess due to paradoxical emboli which mostly seen in previously undiagnosed PAVMs indicating importance of early diagnosis and timely intervention in PAVM. Computed Tomography Pulmonary Angiography (CTPA) is the diagnostic method of choice in PAVM. We present here a unique case of complex multiple PAVM presented with refractory hypoxemia in a middle aged patient diagnosed in our centre initially evaluated for malignancy based on chest radiography & High Resolution Computed tomography(HRCT)thorax findings and symptoms, later on after CTPA was diagnosed to have complex PAVM which showed clinicoradiological improvement following pulmonary vascular plugging. This case shows clinical scenario, diagnostic & management methods and differential diagnosis to be discussed in similar clinicoradiological pattern and peculiarity of PAVM despite advanced age.
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