Garin-kol Avrahami Reut, Zerbib Olivier, Gafter Gvili Anat, Lev Shaul, G. Sahaf levin, Gottesman Tamar
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引用次数: 0
摘要
立克次体是一组革兰氏阴性细胞内专性细菌。立克次体是人类和动物传染病的重要病原体。跳蚤、蜱虫、螨虫、虱子等是将立克次体从动物传染给人类的媒介。立克次体病是已知最古老的媒介传播疾病之一(Blanda等人,2020年)。通常是一种无主要并发症的非特异性自限性发热性疾病。发烧、头痛、轻度皮疹、肌痛和厌食是最常见的症状和体征。实验室结果包括转氨酶水平升高、低钠血症、血小板减少症和贫血(Merhej et al., 2014)。这种病通常是良性的。约6%的病例报告出现严重并发症。患者可能出现器官受累、严重血管炎和多器官衰竭(Oteo and Portillo, 2012),死亡率高达2.5%(Giammanco et al., 2005;Raoult et al., 1986)。
A Case of Rickettsiosis in a Patient with Glucose-6-Phosphate Dehydrogenase (G6pd) Deficiency
Rickettsia is a group of Gram-negative intra cellular obligatory bacteria. Rickettsia species are an important cause of infectious disease in people and animals. Fleas, ticks, mite, lice etc., serve as vectors who transfer the rickettsia from animal to humans.Rickettsiosis is one of the oldest known vector-borne diseases(Blanda et al., 2020).
Usually it is a nonspecific self-limiting febrile illness without major complications. Fever, headache, mild-rash, myalgia's and anorexia are the most common presenting signs and symptoms. Laboratory findings include elevated transaminase levels, hyponatremia, thrombocytopenia and anemia (Merhej et al., 2014).
The disease is usually of benign nature. Severe complications are reported in about 6% of cases. Patients may present with organ involvement, severe vasculitis and multi organ failure (Oteo and Portillo, 2012) and the mortality rate is up to 2.5%(Giammanco et al., 2005; Raoult et al., 1986).