大蒜提取物负载氧化锌纳米颗粒体外抗肌囊虫作用的研究

Sawsan Darwish Jari, Sura Waleed Yasir, Saja Alaa Razzaq
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引用次数: 0

摘要

本研究旨在探讨大蒜提取物负载氧化锌纳米颗粒对体外肌囊虫生存能力的影响,将研究样品分为三组,每组20只(5个培养皿),每个培养皿中含有不同浓度的磷酸盐缓冲盐水(PBS)。实验组以1种混合纳米颗粒(大蒜提取物负载氧化锌纳米颗粒)浓度(0.1、0.3、0.5)mg/ml,在4°C下处理,观察5天的存活率。卡尔巴拉大学兽医学院的SEM(扫描电子显微镜)检测结果表明,在氧化锌纳米颗粒表面加载大蒜提取物的工艺是成功的,混合纳米颗粒在高浓度0.5 mg/ml时对寄生虫的死亡率达到100%,其次是0.3 mg/ml时(8.98%)和0.1mg/ml时(17.66%)。统计分析结果显示,各浓度下死亡率均有显著升高。
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Effect of garlic extract loaded on zinc oxide nanoparticles against Sarcocystis in vitro
The present study aimed to investigate the effect of garlic extract loaded on zinc oxide nanoparticles on the viability of Sarcocystis in vitro Samples of the parasite in the study was divided into three group inside to control group each one consists of 20 parasite in petri dish (5 petri dish) for each concentration contain the Phosphate Buffer Saline(PBS). The group treated with one concentration of the hybrid nanoparticles (Garlic extract loaded on zinc oxide nanoparticles) (0.1, 0.3, 0.5) mg/ml in 4 ᵒC and noticed the viability for five days. The nanoparticle measuring by SEM (Scaning Electronic Microscop) in Karbala University, College of Veterinary Medicine, the results showed that process of loading garlic Extract on the surface of zinc oxide nanoparticles was succeed and the hybrid nanoparticles had great effect (100%) in mortality of the parasite in high concentration 0.5 mg/ml followed by 0.3 mg/ml (8.98%) and (17.66%) in 0.1mg/ml. The statistical analytic results showed that there was significant increasing in mortality in all concentrations.
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来源期刊
CiteScore
0.60
自引率
0.00%
发文量
50
审稿时长
12 weeks
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