{"title":"棒状革兰氏阴性医院获得性细菌感染的发生率和抗生素耐药性:一项基于回顾性人群的研究","authors":"Kamal Jalal Rashid","doi":"10.24017/science.2020.ichms2020.9","DOIUrl":null,"url":null,"abstract":"The gram-negative, especially rod shapes vary in the frequencies that they cause the most frequent types of hospital-acquired infection: pneumonia, surgical site infection, urinary tract infection, diabetic infection, burn and bloodstream infection. The presented study determined the microbial spectrum and antimicrobial susceptibility of gram-negative bacteria isolated from various infection sites in hospitalized patients in Sulaimani city. This study included 735 patients who underwent surgical and wound treatment admitted to the hospital. A microbiological standard technique was used for Identification, isolation and antimicrobial susceptibility. The data in this job were scaled into excel sheets and transferred to SPSS (Statistical Package for Social Sciences) version 24.0 software. The significance of associations between variables and predictor done by Chi-square (χ2). P-value of <0.05 was regarded significant. Male was the most common cases 52.5%. Patients less than 18 years-old were the most frequently affected 54.3%. Gram negative infection is the most common and most serious complication of burn injuries and it is the majority suspected clinical finding nearly to 60%. The most common bacteria separatedd from wound and sepsis were Pseudomonas aeruginosa 91.91%. Individual pathogens’ incidence differ significantly between location of infection p<0.001. Pseudomonas aeruginosa, only resistant stabled at the lowest rates for Colistine and Imepenim (0.1% and 7.8%) and significant finding was confirmed p<0.001. But highly resistance to Ticarcillin/Clavulanic Acid, Cefepime, Tobramycin, and Gentamicin (85.6%, 80.8%, 79.3%, 79.2%) .In conclusion, these population-based study gram-negative infections predominate in burn wounds. Microbial resistance to the confirmed drugs leads to repeated antimicrobial treatment modifications and long-time of treatments.","PeriodicalId":17866,"journal":{"name":"Kurdistan Journal of Applied Research","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Incidence of Rod Shaped Gram-negative Hospital Acquired Bacterial Infection and Antibiotic Resistance: A Retrospective Based Population Study\",\"authors\":\"Kamal Jalal Rashid\",\"doi\":\"10.24017/science.2020.ichms2020.9\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The gram-negative, especially rod shapes vary in the frequencies that they cause the most frequent types of hospital-acquired infection: pneumonia, surgical site infection, urinary tract infection, diabetic infection, burn and bloodstream infection. The presented study determined the microbial spectrum and antimicrobial susceptibility of gram-negative bacteria isolated from various infection sites in hospitalized patients in Sulaimani city. This study included 735 patients who underwent surgical and wound treatment admitted to the hospital. A microbiological standard technique was used for Identification, isolation and antimicrobial susceptibility. The data in this job were scaled into excel sheets and transferred to SPSS (Statistical Package for Social Sciences) version 24.0 software. The significance of associations between variables and predictor done by Chi-square (χ2). P-value of <0.05 was regarded significant. Male was the most common cases 52.5%. Patients less than 18 years-old were the most frequently affected 54.3%. Gram negative infection is the most common and most serious complication of burn injuries and it is the majority suspected clinical finding nearly to 60%. The most common bacteria separatedd from wound and sepsis were Pseudomonas aeruginosa 91.91%. Individual pathogens’ incidence differ significantly between location of infection p<0.001. Pseudomonas aeruginosa, only resistant stabled at the lowest rates for Colistine and Imepenim (0.1% and 7.8%) and significant finding was confirmed p<0.001. But highly resistance to Ticarcillin/Clavulanic Acid, Cefepime, Tobramycin, and Gentamicin (85.6%, 80.8%, 79.3%, 79.2%) .In conclusion, these population-based study gram-negative infections predominate in burn wounds. 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引用次数: 0
摘要
革兰氏阴性菌,特别是杆状菌的频率各不相同,它们引起最常见的医院获得性感染类型:肺炎、手术部位感染、尿路感染、糖尿病感染、烧伤和血液感染。本研究测定了从苏莱曼尼市住院患者不同感染部位分离的革兰氏阴性菌的微生物谱和抗菌药物敏感性。本研究包括735名接受手术和伤口治疗的住院患者。采用微生物标准技术进行鉴定、分离和药敏试验。本作业中的数据被缩放成excel表格,并转移到SPSS (Statistical Package for Social Sciences) 24.0版软件中。变量与预测因子之间相关性的显著性采用χ2表示。p值<0.05为显著性。男性为最常见的病例,占52.5%。18岁以下的患者最常见,占54.3%。革兰氏阴性感染是烧伤最常见和最严重的并发症,是临床上最常见的疑似病例,约占60%。伤口和脓毒症中最常见的细菌为铜绿假单胞菌(91.91%)。不同感染部位的病原菌发病率差异有统计学意义(p<0.001)。铜绿假单胞菌仅对粘菌素和伊美培宁的耐药率最低(分别为0.1%和7.8%),显著性发现p<0.001。但对替卡西林/克拉维酸、头孢吡肟、妥布霉素和庆大霉素高度耐药(85.6%、80.8%、79.3%、79.2%)。结论:革兰氏阴性感染主要发生在烧伤创面。微生物对已确认的药物产生耐药性,导致反复修改抗微生物治疗方案和延长治疗时间。
Incidence of Rod Shaped Gram-negative Hospital Acquired Bacterial Infection and Antibiotic Resistance: A Retrospective Based Population Study
The gram-negative, especially rod shapes vary in the frequencies that they cause the most frequent types of hospital-acquired infection: pneumonia, surgical site infection, urinary tract infection, diabetic infection, burn and bloodstream infection. The presented study determined the microbial spectrum and antimicrobial susceptibility of gram-negative bacteria isolated from various infection sites in hospitalized patients in Sulaimani city. This study included 735 patients who underwent surgical and wound treatment admitted to the hospital. A microbiological standard technique was used for Identification, isolation and antimicrobial susceptibility. The data in this job were scaled into excel sheets and transferred to SPSS (Statistical Package for Social Sciences) version 24.0 software. The significance of associations between variables and predictor done by Chi-square (χ2). P-value of <0.05 was regarded significant. Male was the most common cases 52.5%. Patients less than 18 years-old were the most frequently affected 54.3%. Gram negative infection is the most common and most serious complication of burn injuries and it is the majority suspected clinical finding nearly to 60%. The most common bacteria separatedd from wound and sepsis were Pseudomonas aeruginosa 91.91%. Individual pathogens’ incidence differ significantly between location of infection p<0.001. Pseudomonas aeruginosa, only resistant stabled at the lowest rates for Colistine and Imepenim (0.1% and 7.8%) and significant finding was confirmed p<0.001. But highly resistance to Ticarcillin/Clavulanic Acid, Cefepime, Tobramycin, and Gentamicin (85.6%, 80.8%, 79.3%, 79.2%) .In conclusion, these population-based study gram-negative infections predominate in burn wounds. Microbial resistance to the confirmed drugs leads to repeated antimicrobial treatment modifications and long-time of treatments.