Rate of Adenovirus Infection in Patients with End Stage Renal Disease in Kirkuk Governorate

Adenovirus is a DNA virus which was discovered in 1950s from military recruit with atypical pneumonia. The majority of the higher-level number for serotypes has been insulated from immunocompromised persons. While the majority of infections linked to adenovirus are self-limiting, those who occur in immunocompromised individual can be far more serious, even deadly. Patients who have reached the end of their kidney function have weakened immune response, due to high rates of infection by virus. The goal of this research was to find out the infection with adenovirus in terminal stage of kidney disease patients who undergoing hemodialysis. This study was done in Kirkuk General Hospital/Dialysis Unit in Kirkuk city from the period 12/11/2019 to 5/5/2020. Serum of 200 hemodialysis patients were investigated for both adenovirus-specific immunoglobulin G and M by using enzyme-linked immunosorbent assay (ELISA),108 (54%) patients were males and 92 (46%) were females. The results showed that 142 patients (71%) had anti-adenovirus IgG, 10 patients (5%) had anti-adenovirus IgM and 6 patients (3%) had both anti-IgM and anti-IgG. There was no significant variance in adenovirus seropositivity (p>0.05) between males and females (51.26% and 48.74% respectively). The study showed that non-significant relation between the seropositivity and sex, age and residency. We advise to do adenovirus detection test to those patients who undergone dialysis to decrease the rate of adenoviruses contagion and to avoid renal transplantation failure.