{"title":"Uji Flavonoid Total dan Antioksidan Kulit Batang Balik Angin (Alphitonia excelsa (Fenzl) Reis Ex. Endl)","authors":"Samsul Hadi, Ana Muliana, Amalia Khairunnisa","doi":"10.24123/mpi.v4i2.5208","DOIUrl":null,"url":null,"abstract":"\n \n \n \n \n \n \n \nAlphitonia excelsa merupakan salah satu tanaman yang berpotensi sebagai antioksidan dan telah digunakan secara turun temurun di masyarakat sebagai terapi berbagai macam penyakit. Hal tersebut mendasari tujuan penelitian ini, yaitu menentukan aktivitas antioksidan dan total flavonoid kulit batang A. excelsa. Metode yang di gunakan dalam pengujian antioksidan adalah peredaman terhadap radikal 2,2-difenil-1-pikrilhidrazil (DPPH), sedangkan pengujian flavonoid total dengan AlCl3 dilakukan secara kolorimetri. Hasil yang didapatkan dari penelitian ini adalah nilai IC50 aktivitas antioksidan A. excelsa sebesar 37,00 ± 1,46 μg/ml (bpj) dan flavonoid total senilai 1,17% ± 0.04 QE (quercetin equivalent). Berdasarkan nilai tersebut dapat disimpulkan bahwa kulit batang A. excelsa memiliki kemampuan antioksidan yang sangat kuat. \n \n \n \n \n \n \n \n \n \n \n \n \n \nAlphitonia excelsa is a plant that potential to be tested for its antioxidant ability and has been used as medicine. This underlies the purpose of this study, namely to determine the antioxidant activity and total flavonoids of the stem bark of A. excelsa. The method used in antioxidant evaluaion was 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, while the total flavonoid assay with AlCl3 was carried out colorimetrically. The results obtained from this study were the IC50 value of the antioxidant activity and total flavonoids of A. excelsa, with the value of 37.00 ± 1.46 μg/ml and 1.17% ± 0.04 quercetin equivalent, respectively. Based on these values, it can be concluded that the stem bark of A. excelsa has a very strong antioxidant capacity. \n \n \n \n \n \n \n \n \n \n \n \n","PeriodicalId":18807,"journal":{"name":"MPI (Media Pharmaceutica Indonesiana)","volume":"11 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"MPI (Media Pharmaceutica Indonesiana)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24123/mpi.v4i2.5208","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
Alphitonia excelsa是一种潜在的抗氧化剂植物,它被广泛用于各种疾病的治疗。这是这项研究的目标,即确定抗氧化物和全黄酮活性A. excelsa皮肤。抗氧化剂测试中使用的方法是缓解正基2,二苯-1- pikril液压(DPPH),而完全与AlCl3的flavonoid测试是共重度的。螺旋藻的这项研究的结果是价值大小的圆A。抗氧化能力37,00±1,46草根阶层μg / ml()和类黄酮总共价值1,17%±0。04 QE (quercetin哪里)。根据这些值,可以得出结论,茎A. excelsa具有很强的抗氧化剂能力。Alphitonia是一种可能测试其抗氧化性能力并作为药物使用的植物。这项研究的目的不足,需要确定抗氧化剂活性和总正确性的正确性。用于抗氧化剂评估的方法是2,2- 1-picrylhydrazyl (dpplhydrazyl, dpp3)的全黄酮结探(AlCl3)。The results螺旋藻价值》获得来自这个研究是antioxidant活动和援助总计flavonoids of A价值》圆里,用37点±1μg / ml和46。17%±0。04 quercetin哪里,respectively。基于这些价值,它可以得出结论,excelsa的干细胞具有很强的抗氧化剂电容器结构。
Uji Flavonoid Total dan Antioksidan Kulit Batang Balik Angin (Alphitonia excelsa (Fenzl) Reis Ex. Endl)
Alphitonia excelsa merupakan salah satu tanaman yang berpotensi sebagai antioksidan dan telah digunakan secara turun temurun di masyarakat sebagai terapi berbagai macam penyakit. Hal tersebut mendasari tujuan penelitian ini, yaitu menentukan aktivitas antioksidan dan total flavonoid kulit batang A. excelsa. Metode yang di gunakan dalam pengujian antioksidan adalah peredaman terhadap radikal 2,2-difenil-1-pikrilhidrazil (DPPH), sedangkan pengujian flavonoid total dengan AlCl3 dilakukan secara kolorimetri. Hasil yang didapatkan dari penelitian ini adalah nilai IC50 aktivitas antioksidan A. excelsa sebesar 37,00 ± 1,46 μg/ml (bpj) dan flavonoid total senilai 1,17% ± 0.04 QE (quercetin equivalent). Berdasarkan nilai tersebut dapat disimpulkan bahwa kulit batang A. excelsa memiliki kemampuan antioksidan yang sangat kuat.
Alphitonia excelsa is a plant that potential to be tested for its antioxidant ability and has been used as medicine. This underlies the purpose of this study, namely to determine the antioxidant activity and total flavonoids of the stem bark of A. excelsa. The method used in antioxidant evaluaion was 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, while the total flavonoid assay with AlCl3 was carried out colorimetrically. The results obtained from this study were the IC50 value of the antioxidant activity and total flavonoids of A. excelsa, with the value of 37.00 ± 1.46 μg/ml and 1.17% ± 0.04 quercetin equivalent, respectively. Based on these values, it can be concluded that the stem bark of A. excelsa has a very strong antioxidant capacity.