Assessment of Nano-toxicity and Safety Profiles of Silver Nanoparticles

Nanotoxicology, which is related with toxic potentials of nanoparticles (NPs) and their adverse effects on living organisms and environment, is a sub-branch of toxicology discipline. Nano-toxicity of NPs depends on their doses, unique chemical, and physical prop- erties. Nowadays, silver (Ag) NPs are used in many consumer and scientific applications such as antimicrobial and pharmaceutical applications, water purification systems, tex- tile industry, and food packaging processes. However, the information that about their nano-toxic potentials is still not complete, and it is considered that several parameters of Ag NPs such as size, shape, surface, and stability affect the toxic potential in different ways. Nano-toxic potentials of Ag NPs were mentioned as in vivo , in vitro and in silico the studies. In this chapter, it was evaluated the common unique properties of NPs are related with nanotoxicology such as size, surface area and modifications, shape, agglomeration status, dose.