子宫内膜癌的微囊性、细长和碎片化侵袭:对精确和个性化治疗策略的可能预后价值。

IF 1.1 Q2 MEDICINE, GENERAL & INTERNAL Medeniyet medical journal Pub Date : 2022-12-28 DOI:10.4274/MMJ.galenos.2022.39024

Christos Iavazzo, Alexandros Fotiou, Ioannis D Gkegkes, Nikolaos Vrachnis

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Microcystic Elongated and Fragmented Pattern Invasion in Endometrial Cancer: Possible Prognostic Value to Precise and Individualized Therapeutic Strategies.

the invasive front of the MELF pattern and concluded that programed cell death protein 1/PD-L1 immunotherapy demonstrated significant therapeutic effect on the management of patients with endometrial cancer and grade 1 MELF. Furthermore, Rabe et al. 4 claimed that cytokeratin IHC staining could detect malignant cells in the sentinel lymph nodes of patients with endometrial cancer and MELF. Finally, in a large cohort study, He et al. 5 revealed that participants with POLE-mutated tumors and MELF pattern invasion had a 15.1-fold increase in tumor recurrence or progression risk than POLE-wild type tumors. Once again, we thank the authors for their excellent study.

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来源期刊

Medeniyet medical journal Medicine-Medicine (all)

CiteScore

1.70

自引率

0.00%

发文量

审稿时长

5 weeks

期刊介绍： The Medeniyet Medical Journal (Medeniyet Med J) is an open access, peer-reviewed, and scientific journal of Istanbul Medeniyet University Faculty of Medicine on various academic disciplines in medicine, which is published in English four times a year, in March, June, September, and December by a group of academics. Medeniyet Medical Journal is the continuation of Göztepe Medical Journal (ISSN: 1300-526X) which was started publishing in 1985. It changed the name as Medeniyet Medical Journal in 2015. Submission and publication are free of charge. No fees are asked from the authors for evaluation or publication process. All published articles are available online in the journal website (www.medeniyetmedicaljournal.org) without any fee. The journal publishes intradisciplinary or interdisciplinary clinical, experimental, and basic researches as well as original case reports, reviews, invited reviews, or letters to the editor, Being published since 1985, the Medeniyet Med J recognizes that the best science should lead to better lives based on the fact that the medicine should serve to the needs of society, and knowledge should transform society. The journal aims to address current issues at both national and international levels, start debates, and exert an influence on decision-makers all over the world by integrating science in everyday life. Medeniyet Med J is committed to serve the public and influence people’s lives in a positive way by making science widely accessible. Believing that the only goal is improving lives, and research has an impact on people’s lives, we select the best research papers in line with this goal.