药理学认知增强:当前科学证据下的生物伦理意义

Mijail Alejandro Tapia Moreno
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引用次数: 2

摘要

认知增强药物的使用是目前需要特别关注的一个话题,特别是考虑到患者对处方的需求不断增长。必须检查使用这些药物所固有的伦理方面,特别是当它们不是无害的干预措施时。这些增强认知能力的药物的有效性缺乏科学证据来支持它们的好处,比如更专注或更好的记忆力,因为研究结果显示,在某些任务中,从有害影响到有益影响的范围几乎没有一致性。考虑到这一背景,很明显,需要对处方或推荐它们的道德程度进行评估。这种评估可以根据非恶意、仁慈、自主和正义的生命伦理原则来进行。在审查潜在的不利影响时,非恶意性是一个值得关注的问题。益处尚不清楚,特别是当一些研究中显示的益处是否能转化为现实世界中表现的改善时,更是令人怀疑。虽然目前认知增强药物的有效性表明它们不会对正义原则构成问题,但考虑到这可能会随着更有效的认知增强药物的发展而改变,这一点不应被忽视。
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Mejoramiento cognitivo farmacológico: implicaciones bioéticas a la luz de la evidencia científica actual

The use of cognition-enhancing drugs is a topic that currently requires special attention, particularly given the growing patient demand for their prescription. It is essential to examine the ethical aspects inherent to the use of these drugs, especially when they are not an innocuous intervention.

The effectiveness of these cognition-enhancing drugs lacks the scientific evidence that supports the benefits attributed to them, such as more focus or better memory, as the results in studies show little consistency covering a spectrum from deleterious effects to beneficial effects in certain tasks.

Considering this background, it is obvious that an assessment is required on how ethical it is to prescribe or recommend them. This assessment can be made based on bioethical principles of non-maleficence, beneficence, autonomy, and justice. Non-maleficence is a concern when reviewing potential adverse effects. Beneficence is unclear, particularly when it is doubtful that the benefits shown in some studies translate into improved performance in the real world. Although the current effectiveness of cognition-enhancing drugs suggests that they do not pose a problem to the justice principle, this should not be an aspect to be dismissed considering that this may change with the development of more effective cognition-enhancing drugs.

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