罗马尼亚骨质疏松症患者是否应该进行肌肉减少症筛查?关于骨骼肌减少症的最新知识综述

Q4 Pharmacology, Toxicology and Pharmaceutics Acta Marisiensis - Seria Medica Pub Date : 2023-06-01 DOI:10.2478/amma-2023-0014
Gabriela Mihai, I. Pașcanu
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引用次数: 0

摘要

骨质疏松症与骨骼肌减少症合并症被更广泛地称为“骨骼肌减少症”,被认为是对患者的“危险二重唱”。与骨质疏松症或肌肉减少症相比,这种老年综合征的临床后果包括骨折和死亡风险更高。从经济角度来看,骨折被认为是患者的负担,也是医疗保健系统的负担,因此预防骨折很重要。新出现的证据表明,骨骼肌减少症是一种越来越普遍的疾病。骨折风险评估工具(FRAX)对患者的管理非常重要,然而,肌肉无力不是该工具的一部分。有人建议在治疗持续性脆性骨折患者时,“超越FRAX”,除了评估骨矿物质密度外,还要评估肌肉质量/力量。在这篇综述中,我们试图回答这在罗马尼亚患者中是否可行。
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Should we screen for sarcopenia in Romanian patients with osteoporosis? An overview of the current knowledge on osteosarcopenia
Abstract The combination of osteoporosis and sarcopenia is wider known as “osteosarcopenia”, and it is considered to be a “hazardous duet” for the patient. The clinical consequences of this geriatric syndrome include a higher risk of fractures and mortality compared to osteoporosis or sarcopenia alone. Fractures are considered to be a burden for the patient but also for the health care system from an economic point of view, therefore it is important to prevent them. Emerging evidence shows that osteosarcopenia is an increasingly prevalent disease. The Fracture Risk Assessment Tool (FRAX) is of major importance for the management of a patient, however, muscle weakness is not part of this instrument. It has been suggested to go “beyond the FRAX” and to evaluate muscle mass/strength besides bone mineral density when it comes to the management of a patient with a sustained fragility fracture. In this review we try to answer whether this is feasible or not when it comes to Romanian patients.
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来源期刊
Acta Marisiensis - Seria Medica
Acta Marisiensis - Seria Medica Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)
CiteScore
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审稿时长
24 weeks
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