1,4 -重氮杂环[2.2.2]辛二乙酸酯:一种合成2,4,5 -三取代咪唑的有效、温和且可重复使用的催化剂

IF 1.4 3区 管理学 Q2 INFORMATION SCIENCE & LIBRARY SCIENCE College & Research Libraries Pub Date : 2021-01-01 DOI:10.22034/CRL.2020.252558.1084
L. Fekri, Maryam Nateghi
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引用次数: 5

摘要

1,4 -二氮杂环[2.2.2]双乙酸辛烷提供了一种环境友好的方法,通过一锅多组分缩合合成2,4,5-三取代咪唑的苯或苯甲酸酯和乙酸铵与各种醛。这些化合物产率高,反应时间短。该催化剂易于回收,可重复使用5次,且活性基本一致。所有合成的化合物都通过物理常数、与真实样品的比较、IR、1H NMR、13C NMR谱和元素分析进行了表征。
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1, 4-Diazabicyclo[2.2.2]octanium diacetate: An effective, mild and reusable catalyst for the synthesis of 2,4,5–trisubstituted imidazoles
1, 4-Diazabicyclo[2.2.2]octanium diacetate supplies an environmentally friendly procedure for the synthesis of 2,4,5-trisubstituted imidazoles through one-pot multicomponent condensation of benzyl or benzoin and ammonium acetate with various aldehydes. These compounds were obtained in high yields and short reaction times. The catalyst could be easily recovered and reused for five cycles with almost consistent activity. All of synthesized compounds were characterized by their physical constant, comparison with authentic samples, IR, 1H NMR, 13C NMR spectroscopy and elemental analysis.
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来源期刊
College & Research Libraries
College & Research Libraries INFORMATION SCIENCE & LIBRARY SCIENCE-
CiteScore
3.10
自引率
22.20%
发文量
63
审稿时长
45 weeks
期刊介绍: College & Research Libraries (C&RL) is the official scholarly research journal of the Association of College & Research Libraries, a division of the American Library Association, 50 East Huron St., Chicago, IL 60611. C&RL is a bimonthly, online-only publication highlighting a new C&RL study with a free, live, expert panel comprised of the study''s authors and additional subject experts.
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