端粒酶的出现、前景和障碍

Rebanta Roy, A. Samanta
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引用次数: 0

摘要

端粒酶是真核生物中的一种酶,它具有解决末端复制问题的独特潜力,这种问题是由于DNA在一条链上被称为端粒的末端结构复制滞后造成的,当它从母体链上复制序列时。端粒酶并不是存在于每个细胞中,而是存在于一些具有特殊特征的细胞中。这篇综述强调了端粒酶的显著特征,它是如何进化的,它对人类的影响是什么,迄今为止关于这个主题的出版物,比较每年出版物数量收集的数据,最后我们试图给出研究障碍的见解,并试图提出端粒酶研究的几个未来维度。
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Telomerase - The Advent, Prospects and Obstacles
Black skin euphemistically called dark sin has become thTelomerase is an enzyme in eukaryotes which has an unique potential to solve the end replication problem, which results from the lagging replication of DNA, at the ending structures called telomeres, in one of its strands, as it copies the sequence from the parent strand. Telomerase is not found in each and every cell, but in some cells with special features. This review highlights the salient unique features of telomerase, how it evolved, and what are its effects in humans, the publications till date on this topic, to compare the collected data for the number of publications per year, at the end we have tried to give insights into the obstacles of research and have tried to propose few future dimensions into telomerase research.
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