蛋白质组学和代谢组学:绘制生化调控

Anjum Gahlaut , Vikas , Monika Dahiya , Ashish Gothwal , Mahesh Kulharia , Anil K. Chhillar , Vikas Hooda , Rajesh Dabur
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引用次数: 17

摘要

组学领域的大规模研究已经成功地探索了基因表达、蛋白质和代谢物丰度以及翻译后蛋白修饰的差异,并为细胞中发生的细胞过程提供了不同层次的观点。蛋白质组学和代谢组学是“组学”领域的新成员,但它们都仍在通过评估自己的计算需求来开发自己的计算基础设施。由于对化学信息的深入了解以及将这些化学信息与生物学结果联系起来的重要性,蛋白质组学和代谢组学结合了传统生物信息学和化学信息学的元素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Proteomics & metabolomics: Mapping biochemical regulations

Large-scale studies in the field of omics have been successfully exploring the differences in gene expression, protein and metabolite abundance and modification of post-translational protein, and providing a different level of views for the cellular processes occur in cells. Proteomics and metabolomics are new addition to the ‘omics’ field, but both of them are still developing its own computational infrastructure by assessing the computational needs of its own. Due to the strong knowledge on chemical information and the importance of linking this chemical information to biological consequences, proteomics and metabolomics combines the elements of traditional bioinformatics and cheminformatics.

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