Bilateral Leiomyosarcoma Of The Kidney With Family History Of Bilateral Kidney Cancer: Case Report And Review Of The Literature

We describe an unusual case of bilateral renal leiomyosarcoma in a 61-year-old white man in a patient who presented with a pulmonary emoblism. The patient also had an uncle with bilateral kidney cancer. The patient did not undergo surgery, as the tumor had invaded the surrounding vasculature and was felt to be unresectable by the consulting surgeons. He was treated with gemcitabine and docetaxel chemotherapy, with stabilization of disease. Patient is now stable 10 months after beginning therapy. Sarcomas make up 1–2% of all malignant renal tumors in adult. Bilateral renal leiomyosarcomas are exceedingly rare, with only 17 being reported in the literature. To the best of our knowledge, this is the first reported case of bilateral renal leiomyosarcoma with a family history of bilateral renal cancer.