气相色谱-质谱联用确证月桂叶中毒患者中含有白术皂苷

J.B Laurens , L.C Bekker , V Steenkamp , M.J Stewart
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引用次数: 29

摘要

南非的传统药物金针菇含有线粒体毒素白术苷。这种植物被广泛销售,并继续导致患者死亡。我们首次描述了一种简单的气相色谱-质谱法鉴定白术皂苷的方法,我们已将其应用于中毒患者的洗胃和灵芝提取物。
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Gas chromatographic–mass spectrometric confirmation of atractyloside in a patient poisoned with Callilepis laureola

The South African traditional remedy Impila (Callilepis laureola) contains the mitochondrial toxin atractyloside. The plant is sold widely and continues to lead to fatalities in patients. We describe, for the first time, a simple GC–MS procedure for the identification of atractyloside, which we have applied to the gastric washing from a poisoned patient and to extracts of Impila tuber.

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