罕见儿童非霍奇金淋巴瘤的诊断和治疗

IF 2.2 4区 医学 Q3 HEMATOLOGY Best Practice & Research Clinical Haematology Pub Date : 2023-03-01 DOI:10.1016/j.beha.2023.101440
Ana C. Xavier , Ritsuro Suzuki , Andishe Attarbaschi
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引用次数: 2

摘要

成熟B细胞淋巴瘤、(B或T细胞)淋巴细胞淋巴瘤(LBL)和间变性大细胞淋巴瘤(ALCL)约占儿童和青少年所有非霍奇金淋巴瘤(NHL)病例的90%。剩下的10%包括一组复杂的实体,其特征是发病率低/极低,与成年同行相比,缺乏基本生物学知识,因此缺乏标准化的护理、临床疗效和长期生存信息。在2022年10月20日至23日在美国纽约市组织的第七届儿童、青少年和青年NHL国际研讨会上,我们有机会讨论了某些罕见B细胞或T细胞NHL亚型的临床、病因、诊断和治疗方面,它们将成为本综述的主题。
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Diagnosis and management of rare paediatric Non-Hodgkin lymphoma

Mature B-cell lymphomas, (B- or T-cell) lymphoblastic lymphomas (LBL), and anaplastic large cell lymphoma (ALCL) correspond to about 90% of all non-Hodgkin lymphoma (NHL) cases occurring in children and adolescents. The remaining 10% encompass a complex group of entities characterized by low/very low incidences, paucity of knowledge in terms of underlying biology in comparison to their adult counterparts, and consequent lack of standardization of care, information on clinical therapeutic efficacy and long-term survival. At the Seventh International Symposium on Childhood, Adolescent and Young Adult NHL, organized on October 20–23, 2022, in New York City, New York, US, we had the opportunity to discuss clinical, pathogenetic, diagnostic, and treatment aspects of certain subtypes of rare B- or T-cell NHL and they will be the topic of this review.

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来源期刊
CiteScore
4.20
自引率
0.00%
发文量
42
审稿时长
35 days
期刊介绍: Best Practice & Research Clinical Haematology publishes review articles integrating the results from the latest original research articles into practical, evidence-based review articles. These articles seek to address the key clinical issues of diagnosis, treatment and patient management. Each issue follows a problem-orientated approach which focuses on the key questions to be addressed, clearly defining what is known and not known, covering the spectrum of clinical and laboratory haematological practice and research. Although most reviews are invited, the Editor welcomes suggestions from potential authors.
期刊最新文献
Editorial Board From clones to immunopeptidomes: New developments in the characterization of permissive HLA-DP mismatches in hematopoietic cell transplantation Relevance of donor-specific HLA antibodies in hematopoietic cell transplantation HLA structure and function in hematopoietic-cell transplantation Special issue 37.3: “Genetics and function of HLA and immune-related genes in hematopoietic cell transplantation and cellular immunotherapy”
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