Bladder Cancer Radiation Oncology of the Future: Prognostic Modelling, Radiomics, and Treatment Planning With Artificial Intelligence

Machine learning (ML) and artificial intelligence (AI) have demonstrated potential to improve the care of radiation oncology patients. Here we review recent advances applicable to the care of bladder cancer, with an eye towards studies that may suggest next steps in clinical implementation. Algorithms have been applied to clinical records, pathology, and radiology data to generate accurate predictive models for prognosis and clinical outcomes. AI has also shown increasing utility for auto-contouring and efficient creation of workflows involving multiple treatment plans. As technologies progress towards routine clinical use for bladder cancer patients, we also discuss emerging methods to improve interpretability and reliability of algorithms.