{"title":"心脏移植受者的COVID-19","authors":"Sepideh Taghavi, Hoda Raffiei Jelodar, Ali Rafati, Nasim Naderi, Marzieh Mirtajaddini, Ahmad Amin, Leili Valizadeh, Razieh Omidvar, Monireh Kamali, Soroush Naseh","doi":"10.34172/jcvtr.2022.31583","DOIUrl":null,"url":null,"abstract":"<p><p><b><i>Introduction:</i></b> After solid organ transplantation, patients require lifelong immunosuppressive medication, increasing susceptibility to COVID-19. We evaluated the clinical outcomes of heart transplant recipients in patients with COVID-19. <b><i>Methods:</i></b> We enrolled twenty-two COVID-19 cases of adult heart transplantation from February 2020 to September 2021. <b><i>Results:</i></b> The most common symptoms in patients were fever and myalgia. The death occurred in 3 (13.6 %). <b><i>Conclusion:</i></b> Although heart transplantation mortality may increase in the acute rejection phase concomitant with COVID-19, immunosuppressive dose reduction may not be necessary for all heart transplant patients with COVID-19.</p>","PeriodicalId":15207,"journal":{"name":"Journal of Cardiovascular and Thoracic Research","volume":"14 4","pages":"258-262"},"PeriodicalIF":1.2000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871157/pdf/","citationCount":"8","resultStr":"{\"title\":\"COVID-19 in heart transplant recipients.\",\"authors\":\"Sepideh Taghavi, Hoda Raffiei Jelodar, Ali Rafati, Nasim Naderi, Marzieh Mirtajaddini, Ahmad Amin, Leili Valizadeh, Razieh Omidvar, Monireh Kamali, Soroush Naseh\",\"doi\":\"10.34172/jcvtr.2022.31583\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b><i>Introduction:</i></b> After solid organ transplantation, patients require lifelong immunosuppressive medication, increasing susceptibility to COVID-19. We evaluated the clinical outcomes of heart transplant recipients in patients with COVID-19. <b><i>Methods:</i></b> We enrolled twenty-two COVID-19 cases of adult heart transplantation from February 2020 to September 2021. <b><i>Results:</i></b> The most common symptoms in patients were fever and myalgia. The death occurred in 3 (13.6 %). <b><i>Conclusion:</i></b> Although heart transplantation mortality may increase in the acute rejection phase concomitant with COVID-19, immunosuppressive dose reduction may not be necessary for all heart transplant patients with COVID-19.</p>\",\"PeriodicalId\":15207,\"journal\":{\"name\":\"Journal of Cardiovascular and Thoracic Research\",\"volume\":\"14 4\",\"pages\":\"258-262\"},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2022-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871157/pdf/\",\"citationCount\":\"8\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Cardiovascular and Thoracic Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.34172/jcvtr.2022.31583\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cardiovascular and Thoracic Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.34172/jcvtr.2022.31583","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
Introduction: After solid organ transplantation, patients require lifelong immunosuppressive medication, increasing susceptibility to COVID-19. We evaluated the clinical outcomes of heart transplant recipients in patients with COVID-19. Methods: We enrolled twenty-two COVID-19 cases of adult heart transplantation from February 2020 to September 2021. Results: The most common symptoms in patients were fever and myalgia. The death occurred in 3 (13.6 %). Conclusion: Although heart transplantation mortality may increase in the acute rejection phase concomitant with COVID-19, immunosuppressive dose reduction may not be necessary for all heart transplant patients with COVID-19.