一项比较左炔诺孕酮宫内系统(LNG IUS)和经宫颈子宫内膜切除术(TCRE)治疗月经过多的随机研究:初步结果

Gynaecological Endoscopy Pub Date : 2008-10-09 DOI:10.1046/j.1365-2508.1998.00165.x

Nina Kittelsen, Olav Istre

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引用次数: 62

摘要

目的探讨左炔诺孕酮卷管(mrena;LNG IUS)与经宫颈子宫内膜切除术(TCRE)治疗月经过多。设计一项随机研究，60例患者在妇科诊所进行手术宫腔镜检查。结果LNG IUS组24例，TCRE组29例，随访20个月。在TCRE组中，1例患者在随机化结果后拒绝继续。LNG IUS组停药的原因包括腹痛(2)、痤疮(1)和出血或持续点滴(3)。使用PBAC评分评估出血强度，两组的出血强度均有所降低，LNG IUS组从418降至42,TCRE组从378降至6.6。结论两种方法均可显著降低出血强度，且LNG IUS具有可逆性，无手术危害和副作用。

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A randomized study comparing levonorgestrel intrauterine system (LNG IUS) and transcervical resection of the endometrium (TCRE) in the treatment of menorrhagia: preliminary results

Objective

To identify the effect of the levonorgestrel coil (Mirena; LNG IUS) vs. transcervical resection of the endometrium (TCRE) for treatment of menorrhagia.

Design

A randomized study of 60 patients performed at a gynaecological clinic specializing in operative hysteroscopy.

Results

24 patients in the LNG IUS group and 29 patients in the TCRE group completed 20 months of follow up. In the TCRE group one patient refused to continue after the result of randomization. Reasons for discontinuation in the LNG IUS group included abdominal pain (2), acne (1) and bleeding or continuous spotting (3). The bleeding intensity was assessed using the PBAC score and was reduced in both groups, from 418 to 42 in the LNG IUS group, and from 378 to 6.6 in the TCRE group.

Conclusion

Both methods have a dramatic effect on bleeding intensity and furthermore the LNG IUS is reversible and has no operative hazards or side-effects.

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