Mikael Swarén , Joel Simrén , Hanna Huber , Henrik Zetterberg
{"title":"结合影响监测护齿和血液生物标志物监测泰拳运动员头部影响的案例研究","authors":"Mikael Swarén , Joel Simrén , Hanna Huber , Henrik Zetterberg","doi":"10.1016/j.jsampl.2023.100044","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><p>To investigate the relationship between head impact characteristics and the levels of blood biomarkers associated with brain injury, neurofilament light (NfL) and glial fibrillary acidic protein (GFAP).</p></div><div><h3>Methods</h3><p>Four elite amateur Muay Thai athletes were equipped with impact monitoring mouthguards, collecting linear and rotational acceleration data during a period of eight weeks. Capillary blood samples were collected after each period of sparring sessions to analyse the levels of NfL and GFAP.</p></div><div><h3>Results</h3><p>On a group level, mean GFAP levels were negatively correlated to mean impacts per session (p < 0.05). Two athletes had significant correlations between head impact characteristics and the levels of NfL and/or GFAP.</p></div><div><h3>Conclusions</h3><p>The results indicate that NfL and GFAP might responded differently to linear and rotational accelerations and/or that the effect of different types of accelerations on brain tissue integrity is individual. The methods used could be useful to monitor brain health in different impacts sports.</p></div>","PeriodicalId":74029,"journal":{"name":"JSAMS plus","volume":"2 ","pages":"Article 100044"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S277269672300025X/pdfft?md5=6244d11bd831ed4c717497987f490cf5&pid=1-s2.0-S277269672300025X-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Combining impact monitoring mouthguards and blood biomarkers to monitor head impacts among Muay Thai athletes – A case study\",\"authors\":\"Mikael Swarén , Joel Simrén , Hanna Huber , Henrik Zetterberg\",\"doi\":\"10.1016/j.jsampl.2023.100044\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><p>To investigate the relationship between head impact characteristics and the levels of blood biomarkers associated with brain injury, neurofilament light (NfL) and glial fibrillary acidic protein (GFAP).</p></div><div><h3>Methods</h3><p>Four elite amateur Muay Thai athletes were equipped with impact monitoring mouthguards, collecting linear and rotational acceleration data during a period of eight weeks. Capillary blood samples were collected after each period of sparring sessions to analyse the levels of NfL and GFAP.</p></div><div><h3>Results</h3><p>On a group level, mean GFAP levels were negatively correlated to mean impacts per session (p < 0.05). Two athletes had significant correlations between head impact characteristics and the levels of NfL and/or GFAP.</p></div><div><h3>Conclusions</h3><p>The results indicate that NfL and GFAP might responded differently to linear and rotational accelerations and/or that the effect of different types of accelerations on brain tissue integrity is individual. The methods used could be useful to monitor brain health in different impacts sports.</p></div>\",\"PeriodicalId\":74029,\"journal\":{\"name\":\"JSAMS plus\",\"volume\":\"2 \",\"pages\":\"Article 100044\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S277269672300025X/pdfft?md5=6244d11bd831ed4c717497987f490cf5&pid=1-s2.0-S277269672300025X-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"JSAMS plus\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S277269672300025X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"JSAMS plus","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S277269672300025X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Combining impact monitoring mouthguards and blood biomarkers to monitor head impacts among Muay Thai athletes – A case study
Objective
To investigate the relationship between head impact characteristics and the levels of blood biomarkers associated with brain injury, neurofilament light (NfL) and glial fibrillary acidic protein (GFAP).
Methods
Four elite amateur Muay Thai athletes were equipped with impact monitoring mouthguards, collecting linear and rotational acceleration data during a period of eight weeks. Capillary blood samples were collected after each period of sparring sessions to analyse the levels of NfL and GFAP.
Results
On a group level, mean GFAP levels were negatively correlated to mean impacts per session (p < 0.05). Two athletes had significant correlations between head impact characteristics and the levels of NfL and/or GFAP.
Conclusions
The results indicate that NfL and GFAP might responded differently to linear and rotational accelerations and/or that the effect of different types of accelerations on brain tissue integrity is individual. The methods used could be useful to monitor brain health in different impacts sports.
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