{"title":"碳离子治疗中扫描-被动散射光束的后投影零和收敛arcTAN法确定虚源位置。","authors":"Wan-Bin Meng, Qiang Li, Yan-Cheng Ye, Jia-Ming Wu","doi":"10.3233/XST-221274","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>This study aims to develop and test a new technique by using the convergent arcTAN (cATAN) method capable of dealing with the virtual source position delivered by different carbon ion energies from the pattern of scanning-passive scatter beam.</p><p><strong>Materials and methods: </strong>A homemade large-format CMOS sensor and Gaf Chromic EBT3 films are used for the virtual source position measurement. The Gaf films are embedded in a self-designed rectangular plastic frame to tighten films and set up on a treatment couch for irradiation in air with the film perpendicular to the carbon ion beam at the nominal source-axis-distance (SAD) as well as upstream and downstream from the SAD. The horizontal carbon ion beam with 5 energies at a machine opening field size is carried out in this study. The virtual source position is determined by using the convergent arcTAN (cATAN) method and compared with a linear regression by back projecting FWHM to zero at a distance upstream from the various source-film-distance.</p><p><strong>Results: </strong>The film FWHM measurement error of 0.5 mm leads to 0.001% deviation of α (cATAN) at every assumed textend. The overall uncertainty for the reproducibility of calculated virtual source position by the assumed textend in the vertical and horizontal directions amounts to 0.1%. The errors of calculated virtual source position by assumed textend with back projecting FWHM to zero methods are within 1.1±0.001, p = 0.033.</p><p><strong>Conclusion: </strong>We develop a new technique capable of dealing with the virtual source position with a convergent arcTAN method to avoid any manual measurement mistakes in scanning-passive scatter carbon ion beam. The readers are encouraged to conduct the proposed cATAN method in this study to investigate the virtual source position in the Linac-based external electron beams and the proton beams.</p>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Determination of virtual source position using back projecting zero and convergent arcTAN method for scanning-passive scatter beam in carbon ion therapy.\",\"authors\":\"Wan-Bin Meng, Qiang Li, Yan-Cheng Ye, Jia-Ming Wu\",\"doi\":\"10.3233/XST-221274\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>This study aims to develop and test a new technique by using the convergent arcTAN (cATAN) method capable of dealing with the virtual source position delivered by different carbon ion energies from the pattern of scanning-passive scatter beam.</p><p><strong>Materials and methods: </strong>A homemade large-format CMOS sensor and Gaf Chromic EBT3 films are used for the virtual source position measurement. The Gaf films are embedded in a self-designed rectangular plastic frame to tighten films and set up on a treatment couch for irradiation in air with the film perpendicular to the carbon ion beam at the nominal source-axis-distance (SAD) as well as upstream and downstream from the SAD. The horizontal carbon ion beam with 5 energies at a machine opening field size is carried out in this study. The virtual source position is determined by using the convergent arcTAN (cATAN) method and compared with a linear regression by back projecting FWHM to zero at a distance upstream from the various source-film-distance.</p><p><strong>Results: </strong>The film FWHM measurement error of 0.5 mm leads to 0.001% deviation of α (cATAN) at every assumed textend. The overall uncertainty for the reproducibility of calculated virtual source position by the assumed textend in the vertical and horizontal directions amounts to 0.1%. The errors of calculated virtual source position by assumed textend with back projecting FWHM to zero methods are within 1.1±0.001, p = 0.033.</p><p><strong>Conclusion: </strong>We develop a new technique capable of dealing with the virtual source position with a convergent arcTAN method to avoid any manual measurement mistakes in scanning-passive scatter carbon ion beam. The readers are encouraged to conduct the proposed cATAN method in this study to investigate the virtual source position in the Linac-based external electron beams and the proton beams.</p>\",\"PeriodicalId\":1,\"journal\":{\"name\":\"Accounts of Chemical Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":16.4000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Accounts of Chemical Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3233/XST-221274\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3233/XST-221274","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Determination of virtual source position using back projecting zero and convergent arcTAN method for scanning-passive scatter beam in carbon ion therapy.
Objective: This study aims to develop and test a new technique by using the convergent arcTAN (cATAN) method capable of dealing with the virtual source position delivered by different carbon ion energies from the pattern of scanning-passive scatter beam.
Materials and methods: A homemade large-format CMOS sensor and Gaf Chromic EBT3 films are used for the virtual source position measurement. The Gaf films are embedded in a self-designed rectangular plastic frame to tighten films and set up on a treatment couch for irradiation in air with the film perpendicular to the carbon ion beam at the nominal source-axis-distance (SAD) as well as upstream and downstream from the SAD. The horizontal carbon ion beam with 5 energies at a machine opening field size is carried out in this study. The virtual source position is determined by using the convergent arcTAN (cATAN) method and compared with a linear regression by back projecting FWHM to zero at a distance upstream from the various source-film-distance.
Results: The film FWHM measurement error of 0.5 mm leads to 0.001% deviation of α (cATAN) at every assumed textend. The overall uncertainty for the reproducibility of calculated virtual source position by the assumed textend in the vertical and horizontal directions amounts to 0.1%. The errors of calculated virtual source position by assumed textend with back projecting FWHM to zero methods are within 1.1±0.001, p = 0.033.
Conclusion: We develop a new technique capable of dealing with the virtual source position with a convergent arcTAN method to avoid any manual measurement mistakes in scanning-passive scatter carbon ion beam. The readers are encouraged to conduct the proposed cATAN method in this study to investigate the virtual source position in the Linac-based external electron beams and the proton beams.
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.