从 2011 年到 2020 年,选择性腰椎融合手术的静脉血栓栓塞率并未下降。

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-11-01 Epub Date: 2023-04-28 DOI:10.1177/21925682231173642
Alex Ngan, Junho Song, Austen D Katz, Bongseok Jung, Luke Zappia, Sarah Trent, Jeff Silber, Sohrab Virk, David Essig
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引用次数: 0

摘要

研究设计回顾性队列研究:本研究旨在:(1) 评估 2011 年至 2020 年间 VTE、深静脉血栓 (DVT)、肺栓塞 (PE) 发生率和死亡率的时间趋势;(2) 确定腰椎融合手术后 VTE 的预测因素:方法:计算 2011 年至 2020 年各手术年组 30 天 VTE、DVT、PE 和死亡率的年发生率。利用多变量泊松回归检验手术年份与主要结果之间的关系,并确定VTE的重要预测因素:结果:共纳入了 121 205 名患者。各手术年组间的 VTE、DVT、PE 或死亡率差异无统计学意义。多变量回归分析显示,与2011年相比,2019年手术年的DVT发生率明显较低。年龄、体重指数、手术时间延长、住院时间延长、非居家出院、前路融合、吸烟状况、功能依赖和长期使用类固醇被确定为腰椎融合术后 VTE 的独立预测因素。女性、西班牙裔和门诊手术环境被认为是该队列中VTE的保护因素:结论:2011 年至 2020 年间,腰椎融合术后 VTE 的发生率基本保持不变。年龄越大、体重指数越高、手术时间越长、住院时间越长、非居家出院、前路融合、吸烟、功能依赖和使用类固醇是腰椎融合术后 VTE 的独立预测因素,而女性、西班牙裔和门诊手术则是 VTE 的保护因素。
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Venous Thromboembolism Rates Have Not Decreased in Elective Lumbar Fusion Surgery from 2011 to 2020.

Study design: Retrospective cohort study.

Objectives: This study aimed to (1) evaluate for any temporal trends in the rates of VTE, deep venous thrombosis (DVT), pulmonary embolism (PE), and mortality from 2011 to 2020 and (2) identify the predictors of VTE following lumbar fusion surgery.

Methods: Annual incidences of 30-day VTE, DVT, PE, and mortality were calculated for each of the operation year groups from 2011 to 2020. Multivariable Poisson regression was utilized to test the association between operation year and primary outcomes, as well as to identify significant predictors of VTE.

Results: A total of 121,205 patients were included. There were no statistically significant differences in VTE, DVT, PE, or mortality rates among the operation year groups. Multivariable regression analysis revealed that compared to 2011, operation year 2019 was associated with significantly lower rates of DVT. Age, BMI, prolonged operation time, prolonged length of stay, non-home discharge, anterior fusion, smoking status, functional dependence, and chronic steroid use were identified as independent predictors of VTE following lumbar fusion. Female sex, Hispanic ethnicity, and outpatient surgery setting were identified as protective factors from VTE in this cohort.

Conclusions: Rates of VTE after lumbar fusion have remained mostly unchanged between 2011 and 2020. Older age, higher BMI, longer operation time, prolonged length of stay, non-home discharge, anterior fusion, smoking, functional dependence, and steroid use were independent predictors of VTE after lumbar fusion, while female sex, Hispanic ethnicity, and outpatient surgery were the protective factors.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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