Rafael J García Martínez, Clara Sanz Gea, Víctor Martin-Riera, Armando Raúl Guerra Ruiz, Rosanna Paciucci Barzanti, Roser Ferrer-Costa, Clara Ramirez-Serra
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Dasatinib-Induced Chylothorax: A Clinical Laboratory's Perspective.
Dasatinib is a tyrosine kinase inhibitor drug used for chronic myeloid leukaemia (CML) treatment. Chylothorax has been rarely reported as a secondary effect of dasatinib occurring especially in long-term treated patients, although its pathophysiology is not yet fully understood. Laboratory analysis of the pleural effusion is crucial for chylothorax diagnosis. We report a case of a 53-year-old male patient presenting a chylothorax after 14 years of dasatinib therapy where the clinical laboratory was key in the diagnosis.
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