结构性和先天性心脏缺损经皮联合治疗

Francisco Chamié , Daniel Chamié , Luiz Carlos do Nascimento Simões , Renata Mattos
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摘要

背景:多种先天性缺陷传统上是通过手术矫正的,但现在可以通过经皮治疗。文献中很少有报道证明其有效性和安全性。我们的目的是描述一个经验与联合程序,以治疗不同的先天性和结构性缺陷,在一个单一的治疗会议。方法自2007年起,对不同缺陷进行一次治疗。所有患者均通过超声心动图选择。这些过程是使用已经描述过的针对每个缺陷的传统技术来执行的。结果10例患者,男性5例,年龄1 ~ 67岁,体重11 ~ 90 kg。最常见的孤立性缺损是动脉导管未闭(PDA, n = 5),其次是第二口房间隔缺损(osASD, n = 4)和室间隔缺损(VSD, n = 4)。最常见的组合是VSD合并PDA (n = 2)和VSD合并osASD (n = 2)。2例肺动脉瓣狭窄合并osASD和卵圆孔未闭(PFO), 1例主动脉瓣狭窄合并PDA。此外,闭塞左心房附件PFO和动脉肺动脉瘘与PDA栓塞。所有手术均成功。平均随访31±28.1个月,无2例并发症。没有人员死亡。结论少数报告病例表明,联合手术安全有效,可由经验丰富的专业中心操作人员复制,可作为此类患者的首选治疗方案。
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Combined percutaneous treatment of structural and congenital heart defects

Background

Multiple congenital defects are traditionally corrected surgically, but nowadays can be treated percutaneously. There are few reports in the literature attesting to its efficacy and safety. We aimed to describe an experience with combined procedures to treat different congenital and structural defects, in a single therapeutic session.

Methods

Since 2007, different defects were treated in a single treatment session. All were selected by echocardiography. The procedures were performed using traditional techniques already described for each defect.

Results

Ten patients were treated, five males, aged 1-67 years, weighting 11-90 kilograms. The most prevalent isolated defect was patent ductus arteriosus (PDA, n = 5), followed by ostium secundum atrial septal defects (osASD, n = 4) and ventricular septal defects (VSD, n = 4). The most common combinations were VSD with PDA (n = 2) and VSD with osASD (n = 2). Two pulmonary valve stenosis were dilated with osASD and patent foramen ovale (PFO), and one aortic coarctation with PDA. Additionally, a left atrial appendage with PFO was occluded and an aortopulmonary fistula with PDA was embolized. All procedures were successful. The mean follow-up was 31 ± 28.1 months, with only two complications. There were no deaths.

Conclusions

The small number of reported cases showed that the combined procedures were safe and effective and can be reproduced by experienced operators in specialized centers and may be considered as the first therapeutic option in these patients.

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