在资源有限的情况下,与入住重症监护病房的儿科患者预后相关的因素:横断面研究。

IF 1.7 Q2 PEDIATRICS Pediatric health, medicine and therapeutics Pub Date : 2023-01-01 DOI:10.2147/PHMT.S389404
Getahun Dendir, Nefsu Awoke, Afework Alemu, Ashagrie Sintayhu, Shamill Eanga, Mistire Teshome, Mahlet Zerfu, Mebratu Tila, Blen Kassahun Dessu, Amelework Gonfa Efa, Amanu Gashaw
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引用次数: 1

摘要

背景:重症监护是一门多学科和跨专业的专业,致力于治疗已经或正在发生危及生命的急性器官功能障碍的患者。由于可预防疾病的疾病负荷和死亡率较高,在资源不足的情况下,重症监护病房的患者预后具有挑战性。本研究旨在确定与重症监护病房儿科患者预后相关的因素。方法:在埃塞俄比亚南部Wolaita Sodo和Hawassa大学教学医院进行横断面研究。数据输入和分析使用SPSS版本25。使用Shapiro-Wilk和Kolmogorov-Smirnov数据的正态性检验为正态分布。然后确定不同变量的频率、百分比和交叉表。最后,采用二元logistic回归和多元logistic回归分析其幅度和相关因素。差异有统计学意义,P < 0.05。结果:本研究共纳入396例儿科ICU患者,其中165例(41.7%)死亡。城市地区患者的死亡几率(AOR = 45%, CI 95%: 8%, 67% p值= 0.025)低于农村地区患者。有合并症的患儿(AOR = 9.4, CI 95%: 4.5, 19.7, p = 0.000)比无合并症的患儿更容易死亡。急性呼吸窘迫综合征患者(AOR = 12.86, CI 95%: 4.3, 39.2, p = 0.000)比无急性呼吸窘迫综合征患者更容易死亡。使用机械通气的儿童患者(AOR = 3, CI 95%: 1.7, 5.9, p = 0.000)比不使用机械通气的儿童患者更容易死亡。结论:本研究中儿科ICU患者死亡率较高(40.7%)。合并症、住院、肌力药物的使用和ICU住院时间都是有统计学意义的死亡预测因素。
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Factors Associated with the Outcome of a Pediatric Patients Admitted to Intensive Care Unit in Resource-Limited Setup: Cross-Sectional Study.

Background: Critical care is a multidisciplinary and interprofessional specialty devoted to treating patients who already have or are at danger of developing acute, life-threatening organ dysfunction. Due to the higher disease load and mortality from preventable illness, patient outcomes in intensive care units are challenging in settings with inadequate resources. This study aimed to determine factors associated with outcomes of pediatric patients admitted to intensive care units.

Methods: A cross-sectional study was conducted at Wolaita Sodo and Hawassa University teaching hospitals in southern Ethiopia. Data were entered and analyzed using SPSS version 25. Normality tests using the Shapiro-Wilk and Kolmogorov-Smirnov data were normally distributed. The frequency, percentage, and cross-tabulation of the different variables were then determined. Finally, the magnitude and associated factors were first analyzed using binary logistic regression and then multivariate logistic regression. Statistical significance was set at P < 0.05.

Results: A total of 396 Pediatric ICU patients were included in this study, and 165 (41.7%) deaths were recorded. The odds of patients from urban areas (AOR = 45%, CI 95%: 8%, 67% p-value = 0.025) were less likely to die than those in rural areas. Patients with co morbidities (AOR = 9.4, CI 95%: 4.5, 19.7, p = 0.000) were more likely to die than pediatric patients with no co-morbidities. Patients admitted with Acute respiratory distress syndrome (AOR = 12.86, CI 95%: 4.3, 39.2, p = 0.000) were more likely to die than those with not. Pediatric patients on mechanical ventilation (AOR = 3, CI 95%: 1.7, 5.9, p = 0.000) more likely to die than not mechanically ventilated.

Conclusion: Mortality of paediatric ICU patients was high (40.7%) in this study. Co-morbid disease, residency, the use of inotropes, and the length of ICU stay were all statistically significant predictors of death.

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