加蒂隐球菌脑膜炎合并脑室-腹膜分流的可逆性耳聋和失明:1例报告并文献复习

IF 2.2 4区 医学 Q3 MYCOLOGY Journal de mycologie medicale Pub Date : 2023-05-01 DOI:10.1016/j.mycmed.2023.101357
Anni Wang , Jia Liu , Junyu Liu , Lu Yang , Shiqi Yao , Bang-e Qin , Zhihui Su , Xiaofeng Xu , Han Xia , Ying Jiang , Fuhua Peng
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引用次数: 0

摘要

gattii隐球菌(C.gattii)被认为是热带和亚热带地区免疫活性宿主脑膜炎的主要原因。视觉丧失是常见的,但听力损伤相对罕见的C.gattii脑膜炎。值得注意的是,对病因的研究有限,尤其是对与先天性脑膜炎相关的听觉和眼部并发症的治疗。本文报告一例经脑室-腹腔分流术(VPS)治疗先天性脑膜炎的可逆性耳聋和失明病例。该病例表明,颅内压升高(ICP)可能在加蒂氏菌脑膜炎并发的听力和视力损伤中发挥作用,在开始抗真菌治疗后进行早期VPS手术可以有效改善这种情况下的听力和视觉。
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Reversible deafness and blindness in Cryptococcus gattii meningitis with a ventriculoperitoneal shunt: A case report and literature review

Cryptococcus gattii (C. gattii) has been considered a leading cause of meningitis in immunocompetent hosts in tropical and subtropical regions. Visual loss is common but hearing impairment is relatively infrequent in C. gattii meningitis. Notably, there have been limited studies on the etiology, and especially therapy of auditory and ocular complications associated with C. gattii meningitis. Here we report a case of reversible deafness and blindness treated with a ventriculoperitoneal shunt (VPS) surgery in C. gattii meningitis. This case indicated that elevated intracranial pressure (ICP) may play a role in the concurrent hearing and vision impairments associated with C. gattii meningitis and the early VPS surgery after the initiation of the antifungal therapy may effectively improve both hearing and vision in this condition.

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来源期刊
CiteScore
5.10
自引率
2.80%
发文量
68
审稿时长
6-12 weeks
期刊介绍: The Journal de Mycologie Medicale / Journal of Medical Mycology (JMM) publishes in English works dealing with human and animal mycology. The subjects treated are focused in particular on clinical, diagnostic, epidemiological, immunological, medical, pathological, preventive or therapeutic aspects of mycoses. Also covered are basic aspects linked primarily with morphology (electronic and photonic microscopy), physiology, biochemistry, cellular and molecular biology, immunochemistry, genetics, taxonomy or phylogeny of pathogenic or opportunistic fungi and actinomycetes in humans or animals. Studies of natural products showing inhibitory activity against pathogenic fungi cannot be considered without chemical characterization and identification of the compounds responsible for the inhibitory activity. JMM publishes (guest) editorials, original articles, reviews (and minireviews), case reports, technical notes, letters to the editor and information. Only clinical cases with real originality (new species, new clinical present action, new geographical localization, etc.), and fully documented (identification methods, results, etc.), will be considered. Under no circumstances does the journal guarantee publication before the editorial board makes its final decision. The journal is indexed in the main international databases and is accessible worldwide through the ScienceDirect and ClinicalKey platforms.
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