{"title":"[肠道免疫细胞通过肠-肝轴调控脂肪肝疾病进展的作用]。","authors":"Ping Zhang, Mingxin Zhang, Shilin Cheng, Xin Wang, Hongyan Qin","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Fatty liver disease is one of the most prevalent chronic liver disease worldwide and the gut-liver axis is recognized as increasingly prominent in fatty liver disease. Intestinal dysfunction can affect the occurrence or progression of liver disease, therein, validating the critical role of the intestinal immune cells. Enormous literature reported that macrophages, lymphocyte, dendritic cells (DCs) and other immune cells in the gut as well as their subsets may regulate the fatty liver disease progression via different mechanisms, including disruption of intestinal barrier, dysregulation of intestinal lipid transporters and mediating immune cell migration to liver.</p>","PeriodicalId":23737,"journal":{"name":"Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology","volume":"39 3","pages":"275-280"},"PeriodicalIF":0.0000,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[The role of intestinal immune cells in regulation of fatty liver disease progress through gut-liver axis].\",\"authors\":\"Ping Zhang, Mingxin Zhang, Shilin Cheng, Xin Wang, Hongyan Qin\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Fatty liver disease is one of the most prevalent chronic liver disease worldwide and the gut-liver axis is recognized as increasingly prominent in fatty liver disease. Intestinal dysfunction can affect the occurrence or progression of liver disease, therein, validating the critical role of the intestinal immune cells. Enormous literature reported that macrophages, lymphocyte, dendritic cells (DCs) and other immune cells in the gut as well as their subsets may regulate the fatty liver disease progression via different mechanisms, including disruption of intestinal barrier, dysregulation of intestinal lipid transporters and mediating immune cell migration to liver.</p>\",\"PeriodicalId\":23737,\"journal\":{\"name\":\"Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology\",\"volume\":\"39 3\",\"pages\":\"275-280\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[The role of intestinal immune cells in regulation of fatty liver disease progress through gut-liver axis].
Fatty liver disease is one of the most prevalent chronic liver disease worldwide and the gut-liver axis is recognized as increasingly prominent in fatty liver disease. Intestinal dysfunction can affect the occurrence or progression of liver disease, therein, validating the critical role of the intestinal immune cells. Enormous literature reported that macrophages, lymphocyte, dendritic cells (DCs) and other immune cells in the gut as well as their subsets may regulate the fatty liver disease progression via different mechanisms, including disruption of intestinal barrier, dysregulation of intestinal lipid transporters and mediating immune cell migration to liver.