揭露沉默的杀手:慢性肝病的研究重点。

IF 2 4区 医学 Q3 GASTROENTEROLOGY & HEPATOLOGY Digestive Diseases Pub Date : 2023-03-28 DOI:10.1159/000530349
Yao-Chun Hsu
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引用次数: 0

摘要

慢性肝病(CLD)影响着全球约15亿人非酒精性脂肪性肝病(NAFLD)是最常见的CLD,占流行病例的59%,其次是乙型肝炎病毒(HBV)感染(29%)和丙型肝炎病毒感染(9%)CLD是一种无声杀手,其特点是肝坏死、炎症和纤维化的潜伏进展,最终可导致肝硬化,增加原发性肝癌的风险。根据全球疾病负担研究,2017年有210万人死于CLD,其中肝硬化和肝癌分别占死亡人数的62%和38%。
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Uncovering the Silent Killer: Research highlights on chronic liver diseases.

Chronic liver disease (CLD) affects approximately 1.5 billion people around the world.1 Non-alcoholic fatty liver disease (NAFLD) is the most common CLD that accounts for 59% of prevalent cases, followed by hepatitis B virus (HBV) infection (29%) and hepatitis C virus infection (9%).2 CLD is a silent killer characterized by insidious progression in hepatic necroinflammation and fibrosis that can culminate in cirrhosis and increase the risk of primary liver cancer. According to the Global Burden of Disease study, there were 2.1 million deaths attributable to CLD in 2017, with cirrhosis and liver cancer respectively responsible for 62% and 38% of the mortality.3.

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来源期刊
Digestive Diseases
Digestive Diseases 医学-胃肠肝病学
CiteScore
4.80
自引率
0.00%
发文量
58
审稿时长
2 months
期刊介绍: Each issue of this journal is dedicated to a special topic of current interest, covering both clinical and basic science topics in gastrointestinal function and disorders. The contents of each issue are comprehensive and reflect the state of the art, featuring editorials, reviews, mini reviews and original papers. These individual contributions encompass a variety of disciplines including all fields of gastroenterology. ''Digestive Diseases'' bridges the communication gap between advances made in the academic setting and their application in patient care. The journal is a valuable service for clinicians, specialists and physicians-in-training.
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