每日服用600毫克氟伏沙明缓解难治性强迫症:一例报告。

IF 2.1 3区医学 Q3 PHARMACOLOGY & PHARMACY International Clinical Psychopharmacology Pub Date : 2023-07-01 DOI:10.1097/YIC.0000000000000458

Şengül Kocamer Şahin, Bahadir Demir, Abdurrahman Altindağ

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引用次数: 1

摘要

强迫症(OCD)药物治疗的一线药物是选择性血清素再摄取抑制剂(SSRI)。必须以有效剂量持续用药至少12周才能找到最有效的SSRI。对于治疗，药物剂量应滴定至最高耐受剂量。制造商推荐的氟伏沙明最大剂量为每天300毫克。我们报告了一名强迫症患者耐受600毫克(高剂量)氟伏沙明约1个月后缓解。患者继续使用该剂量3个月，并保持缓解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Remission of treatment-resistant obsessive-compulsive disorder with 600 milligrams of fluvoxamine daily: a case report.

First-line drugs for obsessive-compulsive disorder (OCD) pharmacotherapy are selective serotonin reuptake inhibitors (SSRI). The medication must be continued for at least 12 weeks at an effective dosage to find the most effective SSRI. For treatment, the drug dose should be titrated to the highest tolerated dose. The manufacturer's recommended maximum dose of fluvoxamine is 300 mg per day. We reported remission after about 1 month of 600 mg (high dose) fluvoxamine, which was tolerated by a patient with OCD. The patient continued at this dose for 3 months and remained in remission.

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来源期刊

International Clinical Psychopharmacology 医学-精神病学

CiteScore

4.40

自引率

23.10%

发文量

审稿时长

>12 weeks

期刊介绍： International Clinical Psychopharmacology provides an essential link between research and clinical practice throughout psychopharmacology. It reports on studies in human subjects, both healthy volunteers and patients, which relate the effects of drugs on psychological processes. A major objective of the journal is to publish fully refereed papers which throw light on the ways in which the study of psychotropic drugs can increase our understanding of psychopharmacology. To this end the journal publishes results of early Phase I and II studies, as well as those of controlled clinical trials of psychotropic drugs in Phase II and IV. Other topics covered include the epidemiology of psychotropic drug prescribing and drug taking, the sociology of psychotropic drugs including compliance, and research into the safety and adverse effects of these compounds.