一个环膜锚定E3泛素连接酶基因在番茄中与甾体糖生物碱合成基因共表达。

Tsubasa Shoji, Kazuki Saito
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引用次数: 0

摘要

环膜锚(RMA) E3泛素连接酶参与内质网(ER)相关蛋白降解,介导多种生物内质网驻留酶的调节破坏。我们确定转录因子JASMONATE-RESPONSIVE ETHYLENE RESPONSE factor 4 (JRE4)与番茄中甾体糖生物碱合成基因共同调节rma型连接酶基因SlRMA1的表达,而不是其同源物SlRMA2,可能是为了防止这些代谢物的过度积累。
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A RING membrane-anchor E3 ubiquitin ligase gene is co-expressed with steroidal glycoalkaloid biosynthesis genes in tomato.

RING membrane-anchor (RMA) E3 ubiquitin ligases are involved in endoplasmic reticulum (ER)-associated protein degradation, which mediates the regulated destruction of ER-resident enzymes in various organisms. We determined that the transcription factor JASMONATE-RESPONSIVE ETHYLENE RESPONSE FACTOR 4 (JRE4) co-regulates the expression of the RMA-type ligase gene SlRMA1, but not its homolog SlRMA2, with steroidal glycoalkaloid biosynthesis genes in tomato, perhaps to prevent the overaccumulation of these metabolites.

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