{"title":"在噪音与功能之间:走向非规范翻译组的分类。","authors":"Zachary Ardern, Md Hassan Uz-Zaman","doi":"10.1016/j.cels.2023.04.004","DOIUrl":null,"url":null,"abstract":"<p><p>Eukaryotic genomes are pervasively translated, but the properties of translated sequences outside of canonical genes are poorly understood. A new study in Cell Systems reveals a large translatome that is not under significant evolutionary constraint but is still an active part of diverse cellular systems.</p>","PeriodicalId":54348,"journal":{"name":"Cell Systems","volume":"14 5","pages":"343-345"},"PeriodicalIF":9.0000,"publicationDate":"2023-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Between noise and function: Toward a taxonomy of the non-canonical translatome.\",\"authors\":\"Zachary Ardern, Md Hassan Uz-Zaman\",\"doi\":\"10.1016/j.cels.2023.04.004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Eukaryotic genomes are pervasively translated, but the properties of translated sequences outside of canonical genes are poorly understood. A new study in Cell Systems reveals a large translatome that is not under significant evolutionary constraint but is still an active part of diverse cellular systems.</p>\",\"PeriodicalId\":54348,\"journal\":{\"name\":\"Cell Systems\",\"volume\":\"14 5\",\"pages\":\"343-345\"},\"PeriodicalIF\":9.0000,\"publicationDate\":\"2023-05-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cell Systems\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1016/j.cels.2023.04.004\",\"RegionNum\":1,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell Systems","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1016/j.cels.2023.04.004","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
Between noise and function: Toward a taxonomy of the non-canonical translatome.
Eukaryotic genomes are pervasively translated, but the properties of translated sequences outside of canonical genes are poorly understood. A new study in Cell Systems reveals a large translatome that is not under significant evolutionary constraint but is still an active part of diverse cellular systems.
Cell SystemsMedicine-Pathology and Forensic Medicine
CiteScore
16.50
自引率
1.10%
发文量
84
审稿时长
42 days
期刊介绍：
In 2015, Cell Systems was founded as a platform within Cell Press to showcase innovative research in systems biology. Our primary goal is to investigate complex biological phenomena that cannot be simply explained by basic mathematical principles. While the physical sciences have long successfully tackled such challenges, we have discovered that our most impactful publications often employ quantitative, inference-based methodologies borrowed from the fields of physics, engineering, mathematics, and computer science. We are committed to providing a home for elegant research that addresses fundamental questions in systems biology.
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