Samson E Olerimi, Ehitare I Ekhoye, Oriasotie S Enaiho, Alexander Olerimi
{"title":"尼日利亚郊区社区有感染血血吸虫危险的学龄儿童的选定微量营养素状况","authors":"Samson E Olerimi, Ehitare I Ekhoye, Oriasotie S Enaiho, Alexander Olerimi","doi":"10.4102/ajlm.v12i1.2034","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The parasite <i>Schistosoma haematobium</i> causes urogenital schistosomiasis, a chronic infectious disease that occurs mainly among school-age children.</p><p><strong>Objective: </strong>The prevalence of <i>S. haematobium</i> infection and level of intensity relative to age, gender and status of selected serum micronutrients among school-age children were investigated in suburban communities in Bekwarra, Nigeria.</p><p><strong>Methods: </strong>This cross-sectional school-based study randomly recruited 353 children aged between 4 and 16 years from five elementary schools between June 2019 and December 2019. We gathered socio-demographic data about each child using a semi-structured questionnaire. Blood samples were collected for micronutrient analysis and urine samples were collected for assessment of <i>S. haematobium</i> infection.</p><p><strong>Results: </strong>A total of 57 (16.15%) school-age children were infected with <i>S. haematobium</i>. Girls (<i>n</i> = 34; 9.63%) were more frequently infected than boys (<i>n</i> = 23; 6.52%). Infection was most frequent among children aged 8-11 years (<i>n</i> = 32; 23.19%) and was significantly associated with age (<i>p</i> = 0.022) and gender (<i>p</i> < 0.001). Serum levels of iron, calcium, copper and zinc among infected children were significantly lower than those of non-infected children. Intensity of infection was negatively associated with iron (<i>r</i> = -0.21), calcium (<i>r</i> = -0.24), copper (<i>r</i> = -0.61; <i>p</i> < 0.001) and zinc (<i>r</i> = -0.41; <i>p</i> < 0.002).</p><p><strong>Conclusion: </strong>This study showed that <i>S. haematobium</i> infection adversely impacted the micronutrient status of school-age children in suburban Nigeria. Measures to lower the prevalence of schistosomiasis among school-age children, including efficient drug distribution, education campaigns and community engagement, are necessary.</p><p><strong>What this study adds: </strong>This research emphasises the significance of implementing infection prevention and control interventions to mitigate the transmission and prevalence of schistosomiasis among school age children.</p>","PeriodicalId":45412,"journal":{"name":"African Journal of Laboratory Medicine","volume":null,"pages":null},"PeriodicalIF":1.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244817/pdf/","citationCount":"0","resultStr":"{\"title\":\"Selected micronutrient status of school-aged children at risk of <i>Schistosoma haematobium</i> infection in suburban communities of Nigeria.\",\"authors\":\"Samson E Olerimi, Ehitare I Ekhoye, Oriasotie S Enaiho, Alexander Olerimi\",\"doi\":\"10.4102/ajlm.v12i1.2034\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>The parasite <i>Schistosoma haematobium</i> causes urogenital schistosomiasis, a chronic infectious disease that occurs mainly among school-age children.</p><p><strong>Objective: </strong>The prevalence of <i>S. haematobium</i> infection and level of intensity relative to age, gender and status of selected serum micronutrients among school-age children were investigated in suburban communities in Bekwarra, Nigeria.</p><p><strong>Methods: </strong>This cross-sectional school-based study randomly recruited 353 children aged between 4 and 16 years from five elementary schools between June 2019 and December 2019. We gathered socio-demographic data about each child using a semi-structured questionnaire. Blood samples were collected for micronutrient analysis and urine samples were collected for assessment of <i>S. haematobium</i> infection.</p><p><strong>Results: </strong>A total of 57 (16.15%) school-age children were infected with <i>S. haematobium</i>. Girls (<i>n</i> = 34; 9.63%) were more frequently infected than boys (<i>n</i> = 23; 6.52%). Infection was most frequent among children aged 8-11 years (<i>n</i> = 32; 23.19%) and was significantly associated with age (<i>p</i> = 0.022) and gender (<i>p</i> < 0.001). Serum levels of iron, calcium, copper and zinc among infected children were significantly lower than those of non-infected children. Intensity of infection was negatively associated with iron (<i>r</i> = -0.21), calcium (<i>r</i> = -0.24), copper (<i>r</i> = -0.61; <i>p</i> < 0.001) and zinc (<i>r</i> = -0.41; <i>p</i> < 0.002).</p><p><strong>Conclusion: </strong>This study showed that <i>S. haematobium</i> infection adversely impacted the micronutrient status of school-age children in suburban Nigeria. Measures to lower the prevalence of schistosomiasis among school-age children, including efficient drug distribution, education campaigns and community engagement, are necessary.</p><p><strong>What this study adds: </strong>This research emphasises the significance of implementing infection prevention and control interventions to mitigate the transmission and prevalence of schistosomiasis among school age children.</p>\",\"PeriodicalId\":45412,\"journal\":{\"name\":\"African Journal of Laboratory Medicine\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244817/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"African Journal of Laboratory Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4102/ajlm.v12i1.2034\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"African Journal of Laboratory Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4102/ajlm.v12i1.2034","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
Selected micronutrient status of school-aged children at risk of Schistosoma haematobium infection in suburban communities of Nigeria.
Background: The parasite Schistosoma haematobium causes urogenital schistosomiasis, a chronic infectious disease that occurs mainly among school-age children.
Objective: The prevalence of S. haematobium infection and level of intensity relative to age, gender and status of selected serum micronutrients among school-age children were investigated in suburban communities in Bekwarra, Nigeria.
Methods: This cross-sectional school-based study randomly recruited 353 children aged between 4 and 16 years from five elementary schools between June 2019 and December 2019. We gathered socio-demographic data about each child using a semi-structured questionnaire. Blood samples were collected for micronutrient analysis and urine samples were collected for assessment of S. haematobium infection.
Results: A total of 57 (16.15%) school-age children were infected with S. haematobium. Girls (n = 34; 9.63%) were more frequently infected than boys (n = 23; 6.52%). Infection was most frequent among children aged 8-11 years (n = 32; 23.19%) and was significantly associated with age (p = 0.022) and gender (p < 0.001). Serum levels of iron, calcium, copper and zinc among infected children were significantly lower than those of non-infected children. Intensity of infection was negatively associated with iron (r = -0.21), calcium (r = -0.24), copper (r = -0.61; p < 0.001) and zinc (r = -0.41; p < 0.002).
Conclusion: This study showed that S. haematobium infection adversely impacted the micronutrient status of school-age children in suburban Nigeria. Measures to lower the prevalence of schistosomiasis among school-age children, including efficient drug distribution, education campaigns and community engagement, are necessary.
What this study adds: This research emphasises the significance of implementing infection prevention and control interventions to mitigate the transmission and prevalence of schistosomiasis among school age children.
期刊介绍：
The African Journal of Laboratory Medicine, the official journal of ASLM, focuses on the role of the laboratory and its professionals in the clinical and public healthcare sectors,and is specifically based on an African frame of reference. Emphasis is on all aspects that promote and contribute to the laboratory medicine practices of Africa. This includes, amongst others: laboratories, biomedical scientists and clinicians, medical community, public health officials and policy makers, laboratory systems and policies (translation of laboratory knowledge, practices and technologies in clinical care), interfaces of laboratory with medical science, laboratory-based epidemiology, laboratory investigations, evidence-based effectiveness in real world (actual) settings.
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