具有增强电化学稳定性的二氧化硅杂化酶生物传感器用于葡萄糖的精确检测。

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2023-01-01 DOI:10.1155/2023/6620613

Li Mei, Yiting Yang, Jiagen Li, Shuyong Shang, Xiaohong Fu

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引用次数: 0

摘要

利用逐层组装技术成功研制了一种新型的酶基葡萄糖检测生物传感器。研究发现，引入市售SiO2是提高整体电化学稳定性的一种简便方法。经过30个CV循环后，所提出的生物传感器可以保持95%的原始电流。该传感器具有良好的检测稳定性和重复性，检测浓度范围为1.96 × 10-9 ~ 7.24 × 10-7 M。该研究表明，廉价无机纳米粒子的杂交是一种制备高性能生物传感器的有效方法，而且成本低得多。

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A SiO₂ Hybrid Enzyme-Based Biosensor with Enhanced Electrochemical Stability for Accuracy Detection of Glucose.

A novel enzyme-based biosensor for glucose detection is successfully developed using layer-by-layer assembly technology. The introduction of commercially available SiO₂ was found to be a facile way to improve overall electrochemical stability. After 30 CV cycles, the proposed biosensor could retain 95% of its original current. The biosensor presents good detection stability and reproducibility with the detection concentration range of 1.96 × 10^-9 to 7.24 × 10^-7 M. This study demonstrated that the hybridization of cheap inorganic nanoparticles was a useful method in preparing high-performance biosensors with a much lower cost.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.

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