Y Z Gu, S P He, J J Wu, L Qiao, L D Zhao, M T Li, Y Zhao, X F Zeng
{"title":"[一例模拟Sjögren综合征的Castleman病]。","authors":"Y Z Gu, S P He, J J Wu, L Qiao, L D Zhao, M T Li, Y Zhao, X F Zeng","doi":"10.3760/cma.j.cn112138-20220627-00482","DOIUrl":null,"url":null,"abstract":"患者女性,18岁。喘憋,淋巴结肿大,胸部CT以肺囊性变为主要表现,查IgG 38.00 g/L,红细胞沉降率(ESR)92 mm/1h,超敏C反应蛋白(CRP)16.75 mg/L,抗SSA抗体阳性,最初考虑干燥综合征,予患者泼尼松(30 mg/d)、羟氯喹(0.2 g,2次/d)、吗替麦考酚酯(0.75 g,2次/d)治疗2月余,效果不佳,最终经淋巴结活检病理诊断为Castleman病(浆细胞型),予TCP方案[沙利度胺100 mg每晚1次+环磷酰胺400 mg(第1、8、15、22天)+泼尼松50 mg(第1~2、8~9、15~16、22~23天)]化疗6个月后,患者体重指数保持稳定,食欲正常,运动量较前改善,复查IgG 16.23 g/L,ESR 18 mm/1h,超敏CRP 3.51 mg/L。Castleman病是一种较为少见的淋巴增殖性疾病,本例患者诊断疑难,故对不能完全解释的临床现象或治疗效果不佳的难治病例,应及时思考诊断与治疗的合理性,为患者争取正确诊断、早期治疗的机会。.","PeriodicalId":24000,"journal":{"name":"Zhonghua nei ke za zhi","volume":"62 6","pages":"711-713"},"PeriodicalIF":0.0000,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[A case of Castleman disease mimicking Sjögren's syndrome].\",\"authors\":\"Y Z Gu, S P He, J J Wu, L Qiao, L D Zhao, M T Li, Y Zhao, X F Zeng\",\"doi\":\"10.3760/cma.j.cn112138-20220627-00482\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"患者女性,18岁。喘憋,淋巴结肿大,胸部CT以肺囊性变为主要表现,查IgG 38.00 g/L,红细胞沉降率(ESR)92 mm/1h,超敏C反应蛋白(CRP)16.75 mg/L,抗SSA抗体阳性,最初考虑干燥综合征,予患者泼尼松(30 mg/d)、羟氯喹(0.2 g,2次/d)、吗替麦考酚酯(0.75 g,2次/d)治疗2月余,效果不佳,最终经淋巴结活检病理诊断为Castleman病(浆细胞型),予TCP方案[沙利度胺100 mg每晚1次+环磷酰胺400 mg(第1、8、15、22天)+泼尼松50 mg(第1~2、8~9、15~16、22~23天)]化疗6个月后,患者体重指数保持稳定,食欲正常,运动量较前改善,复查IgG 16.23 g/L,ESR 18 mm/1h,超敏CRP 3.51 mg/L。Castleman病是一种较为少见的淋巴增殖性疾病,本例患者诊断疑难,故对不能完全解释的临床现象或治疗效果不佳的难治病例,应及时思考诊断与治疗的合理性,为患者争取正确诊断、早期治疗的机会。.\",\"PeriodicalId\":24000,\"journal\":{\"name\":\"Zhonghua nei ke za zhi\",\"volume\":\"62 6\",\"pages\":\"711-713\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zhonghua nei ke za zhi\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3760/cma.j.cn112138-20220627-00482\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zhonghua nei ke za zhi","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3760/cma.j.cn112138-20220627-00482","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}