[胃癌DNA未配对核苷酸修复系统受损]。

Q4 Medicine Arkhiv patologii Pub Date : 2023-01-01 DOI:10.17116/patol20238502144

D V Rianzhin, G A Raskin, M S Mukhina, I V Rykov, S O Kusin, O V Khodyreva

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引用次数: 0

摘要

这篇文章提出了一个成功治疗不能手术的胃癌与不匹配的核苷酸修复系统受损(dMMR/MSI-H)在一个72岁的病人。考虑到患者的年龄、身体状况和是否存在合并症，我们决定将抗pd -1治疗作为一线治疗。目前，经过2年的治疗，患者病情稳定缓解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[Gastric cancer with impaired DNA unpaired nucleotide repair system].

This article presents a case of successful treatment of inoperable gastric cancer with impaired mismatched nucleotide repair system (dMMR/MSI-H) in a 72-year-old patient. In view of age, somatic status and the presence of comorbidity, it was decided to prescribe anti-PD-1 therapy in the 1st line of treatment. Currently, after a 2-year course of treatment, the patient is in stable remission.

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来源期刊

Arkhiv patologii Medicine-Pathology and Forensic Medicine

CiteScore

0.90

自引率

0.00%

发文量

期刊介绍： The journal deals with original investigations on pressing problems of general pathology and pathologic anatomy, newest research methods, major issues of the theory and practice as well as problems of experimental, comparative and geographic pathology. To inform readers latest achievements of Russian and foreign medicine the journal regularly publishes editorial and survey articles, reviews of the most interesting Russian and foreign books on pathologic anatomy, new data on modern methods of investigation (histochemistry, electron microscopy, autoradiography, etc.), about problems of teaching, articles on the history of pathological anatomy development both in Russia and abroad.