[心律失常和淀粉样变]。

Jorge Salinas-Arce, Raúl Alca-Clares, Ana Cecilia Gonzales-Luna, Mario Cabrera-Saldaña, Pablo Mendoza-Novoa, Paula Solórzano-Altamirano, Milton Guevara-Valdivia
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引用次数: 0

摘要

心脏淀粉样变性(CA)是一种心肌病,其特征是心肌中蛋白纤维的细胞外沉积,导致心力衰竭、心律失常和电传导系统改变。众所周知,大多数心肌病与心律异常有密切的关系,然而,即使在诊断前阶段,CA也与不同类型的心律失常有特殊的关系。高达70%的CA患者存在心房颤动等心律失常,与心脏栓塞并发症的高风险无关。室性心律失常是常见的,但使用植入式心律转复除颤器尚未被证明可以提高生存率。房室结疾病也很常见,通常与植入起搏器有关,即使在无症状的患者中也是如此。在这篇综述中,我们澄清了最新指南的建议,总结了历史和当代的数据,并描述了心律失常及其并发症的循证管理策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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[Cardiac arrhythmias and amyloidosis].

Cardiac amyloidosis (CA) is a form of cardiomyopathy characterized by the extracellular deposit of protein fibers in the myocardium, leading to the development of heart failure, arrhythmias, and electrical conduction system alterations. It is known that most cardiomyopathies have a close relationship with heart rhythm abnormalities, however, CA is specially related to different kinds of arrhythmias even in pre-diagnosis stages. Arrhythmias like atrial fibrillation are present in up to 70% of patients with CA associated with a high risk of cardioembolic complications independent of the risk stratification. Ventricular arrhythmias are frequent, but the use of implantable cardioverter defibrillator has not been demonstrated to improve survival. The Atrial-Ventricular node disease is also common, and is frequently associated with the implantation of a pacemaker, even in asymptomatic patients. In this review, we clarify the recommendations of the most current guidelines, summarize historical and contemporaneous data and describe evidence-based strategies for the management of arrhythmias and their complications in CA.

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CiteScore
0.40
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审稿时长
4 weeks
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