致死性芽孢梭菌软组织多微生物感染两例免疫功能正常病例报告。

Q3 Pharmacology, Toxicology and Pharmaceutics Infectious disorders drug targets Pub Date : 2023-01-01 DOI:10.2174/1871526523666230112161134

Preeti Chaudhary, Neelam Gulati, Varsha Gupta, Gazal Dhanda, Mani Bhushan Kumar, Swati Sharma, Anku Goel, Ashok Kumar Attri

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引用次数: 1

摘要

背景:产孢梭菌文献报道较少。皮肤和软组织感染的报告甚至更少，在免疫能力强的患者中更是如此。病例介绍:两个皮肤和软组织感染的芽孢杆菌免疫正常的病人已经提出了这项研究。其中一例是电烧伤，另一例是褥疮。尽管进行了抗菌治疗和清创，但两名患者均死亡。讨论与结论:孢子囊菌通常在创伤后，特别是在穿透性和深度伤口感染后报道。应给予这些患者更多的关注，以便在疑似厌氧菌感染(如梭状芽胞杆菌)时及早治疗和诊断感染。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Fatal Clostridium sporogenes Soft Tissue Polymicrobial Infections in Two Immunocompetent Cases: Case Report.

Background: Clostridium sporogenes is reported rarely in literature. Reports from the skin and soft tissue infections are even less, more so in immunocompetent patients.

Case presentation: Two skin and soft tissue infections with C. sporogenes in immunocompetent patients have been presented in this study. One of the cases was following an electrical burn wound, and the other was following a bedsore. Both patients expired despite antibacterial treatment and debridement.

Discussion and conclusion: C. sporogenes had usually been reported after trauma particularly after penetrating and deep wound infection. More attention should be given to these patients so that the infection can be treated and diagnosed early in suspected anaerobic infections like Clostridium species.

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来源期刊

Infectious disorders drug targets Pharmacology, Toxicology and Pharmaceutics-Pharmacology

CiteScore

3.10

自引率

0.00%

发文量

123

期刊介绍： Infectious Disorders - Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular targets involved in infectious disorders e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal contains a series of timely in-depth reviews written by leaders in the field covering a range of current topics on drug targets involved in infectious disorders. As the discovery, identification, characterization and validation of novel human drug targets for anti-infective drug discovery continues to grow, this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.