银纳米颗粒对甲型流感病毒的抗病毒活性

IF 3.5 4区医学 Q2 IMMUNOLOGY Journal of Virus Eradication Pub Date : 2023-06-01 DOI:10.1016/j.jve.2023.100330

Krystyna Naumenko , Svitlana Zahorodnia , Calin V. Pop , Nodari Rizun

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引用次数: 0

摘要

病毒感染在现代医学中占有重要地位，特别是由流感病毒引起的一大群疾病。它们传播迅速，变异迅速，可能导致严重的社会经济后果。银纳米粒子(AgNPs)被认为是一种有效的抗菌药物。本研究表明，它们对甲型流感病毒感染具有较强的抗病毒特性。它们在抑制浓度下没有细胞毒性，表明它们可能是一种有效的抗病毒药物。由于AgNPs抑制甲型流感病毒的复制和传播，它们也可以成功地用作感染后的病毒抑制剂。

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Antiviral activity of silver nanoparticles against the influenza A virus

Viral infections occupy an essential place in modern medicine, particularly a large group of diseases caused by the influenza viruses. They are rapidly transmitted and mutate quickly, which can lead to significant socio-economic consequences. Silver nanoparticles (AgNPs) are considered to be an effective antimicrobial agent. This study shows that they have strong antiviral properties against the influenza A virus infection. Their absence of cytotoxicity at inhibitory concentrations demonstrates that they could be an effective antiviral agent against this virus. As AgNPs inhibit the influenza A virus replication and spread, they could also be successfully used as a post-infection virostatic agent.

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来源期刊

Journal of Virus Eradication Medicine-Public Health, Environmental and Occupational Health

CiteScore

6.10

自引率

1.80%

发文量

审稿时长

39 weeks

期刊介绍： The Journal of Virus Eradication aims to provide a specialist, open-access forum to publish work in the rapidly developing field of virus eradication. The Journal covers all human viruses, in the context of new therapeutic strategies, as well as societal eradication of viral infections with preventive interventions. The Journal is aimed at the international community involved in the prevention and management of viral infections. It provides an academic forum for the publication of original research into viral reservoirs, viral persistence and virus eradication and ultimately development of cures. The Journal not only publishes original research, but provides an opportunity for opinions, reviews, case studies and comments on the published literature. It focusses on evidence-based medicine as the major thrust in the successful management of viral infections.The Journal encompasses virological, immunological, epidemiological, modelling, pharmacological, pre-clinical and in vitro, as well as clinical, data including but not limited to drugs, immunotherapy and gene therapy. It is an important source of information on the development of vaccine programs and preventative measures aimed at virus eradication.