治疗多发性牙龈退缩的新型生物材料高级富血小板纤维蛋白加阻滞剂

IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Clinical Advances in Periodontics Pub Date : 2023-07-07 DOI:10.1002/cap.10257

Jayasheela Mallappa, Leena Patil, Adi Deepika Mani, Triveni M. Gowda

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引用次数: 0

摘要

背景该研究旨在评估和比较使用前庭切口骨膜下隧道入路（VISTA）治疗多发性牙龈退缩时，使用和不使用高级富血小板纤维蛋白+（A-PRF+）阻滞剂进行硬组织和软组织增量的临床放射学效果。方法共纳入 24 名患者，他们的上颌美学区都有多个米勒 I 级或 II 级退缩。参与者分为两组，第一组采用 VISTA & A-PRF+ 阻滞治疗，第二组仅采用 VISTA 技术。临床参数探查深度、角化牙龈宽度、牙龈生物型、退缩深度和临床附着水平在基线和 6 个月结束时均有记录。在基线和术后 6 个月对唇板厚度进行放射锥束计算机断层扫描测量。结果从基线到术后 6 个月，两组患者的临床和统计参数都有所改善。不过，在统计学上，两种治疗方式并没有明显的差异。在组间影像学比较中，6 个月后唇板厚度与基线相比有统计学意义。结论 A-PRF+ 嵌体与 VISTA 技术可以作为一种有效的根面覆盖方法，用于治疗上颌美学区的多发性牙龈凹陷。要点为什么这项研究是新信息？据我们所知，这是首次使用先进的富血小板纤维蛋白加阻滞剂治疗薄唇板多发性牙龈退缩的研究。成功治疗这类病例的关键是什么？微创前庭切口骨膜下隧道入路技术和避免二次手术部位发病是治疗和患者依从性的重要因素。这项研究的主要局限性是什么？研究时间短、样本量小、无组织学相关性可视为本研究的局限性。

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Novel biomaterial advanced platelet-rich fibrin plus block for multiple gingival recession

Background

The study was aimed to assess and compare hard and soft tissue augmentation clinicoradiographically with and without advanced platelet-rich fibrin + (A-PRF+) block for the treatment of multiple gingival recession using vestibular incision subperiosteal tunnel access (VISTA).

Methods

A total of 24 patients, exhibiting multiple Miller's Class I or II recessions in the maxillary esthetic zone were included. Participants were divided into two groups, Group 1 was treated with VISTA & A-PRF+ block whereas Group 2 was with VISTA technique alone. Clinical parameters probing depth, width of keratinized gingiva, gingival biotype, recession depth, and clinical attachment level were recorded at baseline and the end of 6 months. The radiographic cone beam computed tomography measurements of labial plate thickness were taken at baseline and 6 months postoperatively.

Results

From baseline to 6 months both the groups showed a clinical and statistical improvement in the parameters. However, a statistically significant difference between the treatment modalities was not observed. In the inter-group comparison radiographically, labial plate thickness was statistically significant at the end of 6 months when compared to the baseline.

Conclusion

A-PRF+ block along with the VISTA technique can be an alternative effective root coverage procedure for the management of multiple gingival recessions in the maxillary esthetic zone.

Key points

Why is this study new information?

To the best of our knowledge, this is the first study using advanced platelet-rich fibrin plus block for the treatment of multiple gingival recession with a thin labial plate.

What are the keys to the successful management of these types of cases?

Minimally invasive vestibular incision subperiosteal tunnel access technique, and avoidance of second surgical site morbidity are important factors for treatment and for patient compliance.

What are the primary limitations of this study?

Short study duration, small sample size, and no histological correlation can be considered as limitations of the study.

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