免疫状态下播散性肺结核一例报告。

Q3 Pharmacology, Toxicology and Pharmaceutics Infectious disorders drug targets Pub Date : 2023-01-01 DOI:10.2174/1871526522666220921123920
Jitendra Singh, Anju Dinkar, Nitish Kumar Patel, Bhavya J, Ankita Dewangan, Nilesh Kumar, Kalish Kumar
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引用次数: 0

摘要

背景:结核病是人类的主要传染病之一,仍然是一个重大的健康问题,特别是在发展中国家。结核病的临床表现很广泛,有时临床医生很难及早诊断。在免疫功能低下的个体中,腰肌结核性脓肿通常继发于脊柱结核或直接从邻近结构延伸,但免疫功能正常的腰肌结核性脓肿非常罕见。此外,全血细胞减少症和新发颈部肿胀同时出现,使得这种表现在结核病中是非常罕见的临床表现。病例介绍:我们现在报告一个21岁,未婚,其他健康的女孩,表现为发烧,下腹部疼痛和体重下降两个月。她还发现颈部无痛肿胀了15天。根据证据,她后来出现了左侧腰肌结核性脓肿并全血细胞减少,颈部左侧出现冷脓肿,没有其他明显病灶的迹象。没有肺部受累的弥散性结核诊断被确立,并开始了ATT。在后续调查中,结果是成功的。结论:在结核病的广泛非典型表现中,本病例报告提请注意其罕见性、诊断挑战和对临床谱的认识,特别是在发展中国家。
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Disseminated Tuberculosis in an Immunocompetent State: A Case Report.

Background: Tuberculosis is one of the major infectious diseases of mankind and remains a significant health concern, especially in developing countries. Clinical manifestations of TB are broad and sometimes very challenging for clinicians to diagnose early. Tuberculous psoas abscess was generally secondary to spinal tuberculosis or direct extension from adjacent structures in immunocompromised individuals, but tuberculous psoas abscess in the immunocompetent state is very infrequent. In addition, pancytopenia and new onset neck swelling simultaneously make this presentation a very unusual clinical entity in tuberculosis.

Case presentation: We now present a case of a 21-years-old, unmarried, otherwise healthy girl presented with fever, lower abdominal pain and weight loss for two months. She also noticed painless neck swelling for 15 days. She later had a tuberculous left sided psoas abscess with pancytopenia and a cold abscess on the left side of the neck with no sign of any other apparent focus, according to the evidence. Diagnosis of disseminated TB without lung involvement was established and ATT was started. The outcome was successful on follow up.

Conclusion: Among the broad spectrum of atypical manifestations of TB, this case report draws attention to its rarity, diagnostic challenge and awareness of the clinical spectrum, especially in developing countries.

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来源期刊
Infectious disorders drug targets
Infectious disorders drug targets Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
3.10
自引率
0.00%
发文量
123
期刊介绍: Infectious Disorders - Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular targets involved in infectious disorders e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal contains a series of timely in-depth reviews written by leaders in the field covering a range of current topics on drug targets involved in infectious disorders. As the discovery, identification, characterization and validation of novel human drug targets for anti-infective drug discovery continues to grow, this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.
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