膝关节艺术成形术后C蛋白表达水平与性别差异及艺术成形术类型的关系。

IF 1.3 4区 医学 Q3 ORTHOPEDICS Journal of Orthopaedic Surgery Pub Date : 2023-05-01 DOI:10.1177/10225536231190309
Harun Altinayak, Yavuz Selim Karatekin, Orhan Balta
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引用次数: 0

摘要

目的:探讨膝关节置换术后CRP水平与性别差异及置换术类型的关系。方法:检测TKA或UKA患者术前和术后(第1天和第7天、第1个月和第3个月)的CRP值。通过将他们分为原发性男性-女性组和继发性TKA-UKA组对数据进行比较。结果:967名患者被纳入研究(151名男性,TKA组685名女性,25名男性,UKA组106名女性)在TKA组中,男性平均年龄为67.38岁,女性平均年龄为65.54岁。在UKA组中,男性的平均年龄为58.72岁,女性为57,63岁。TKA患者术前、术后第1个月和第3个月,女性的CRP值在统计学上显著低于男性(p<0.05),p<.05)。当根据关节成形术类型评估CRP值及其对关节成术过程的影响时,术前患者的CRP值之间没有显著差异(p=.686)。此外,在术后第1天、第1周、第1个月和第3个月的比较中,接受UKA的患者的CRP值明显较低(p<0.05)。当按关节成形术类型单独分析时,96.3%的TKA患者和98.5%的第三个月接受UKA患者的术后CRP值降至正常范围。结论:我们的研究表明,TKA和UKA后CRP的无并发症过程是性别特异性的,男性的CRP值高于女性。UKA组术后CRP水平明显低于TKA组。
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The relationship of C-reaktif protein level after knee artroplasty with gender difference and type of artroplasty.

Purpose: It was aimed to reveal the relationship between CRP level after knee arthroplasty and gender difference and arthroplasty type.

Methods: Preoperative and postoperative (1st and 7th day, 1st and 3rd months) CRP values of the patients who underwent TKA or UKA were examined. The data were compared by categorizing them into primary male-female, secondary TKA-UKA groups.

Results: 967 patients were included in the study (151 male, 685 female in the TKA group and 25 male, 106 female in the UKA group) In the TKA group, the mean age was 67.38 in males and 65.54 in females. In the UKA group, the mean age was 58.72 in males and 57,63 in females. CRP values were found to be statistically significantly lower in females compared to males in the preoperative period, postoperative 1st and 3rd months in patients who underwent TKA (p < .05). In the UKA group, it was found to be significantly lower in females in the preoperative period and at the postoperative 3rd month, p < .05). When the CRP values and their effect on the course of arthroplasty were evaluated according to the type of arthroplasty, there was no significant difference between the CRP values of the preoperative patients (p = .686). In addition, in the comparison made on the postoperative 1st day, 1st week, 1st month, and 3rd month, CRP values of the patient who underwent UKA were found to be significantly lower (p < .05). When analyzed separately by arthroplasty type, postoperative CRP values decreased to normal limits in 96.3% of patients who underwent TKA and 98.5% of patients who underwent UKA in the third month.

Conclusions: Our study showed that the uncomplicated course of CRP after TKA and UKA is gender-specific, and higher CRP values are observed in males than in females. The UKA group exhibited significantly lower postoperative CRP levels than the TKA group.

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来源期刊
Journal of Orthopaedic Surgery
Journal of Orthopaedic Surgery ORTHOPEDICS-SURGERY
CiteScore
3.10
自引率
0.00%
发文量
91
审稿时长
13 weeks
期刊介绍: Journal of Orthopaedic Surgery is an open access peer-reviewed journal publishing original reviews and research articles on all aspects of orthopaedic surgery. It is the official journal of the Asia Pacific Orthopaedic Association. The journal welcomes and will publish materials of a diverse nature, from basic science research to clinical trials and surgical techniques. The journal encourages contributions from all parts of the world, but special emphasis is given to research of particular relevance to the Asia Pacific region.
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