脑炎和脑膜炎:干预指征。

Clinical research (Westerville, Ohio) Pub Date : 2023-01-01 Epub Date: 2023-04-26
Abeer Dagra, Mac Lyerly, Brandon Lucke-Wold
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引用次数: 0

摘要

脑膜炎和脑炎分别以脑膜和脑实质发炎为特征。血脑屏障通常是中枢神经系统(CNS)抵御炎症的保护屏障,但其受损需要及时诊断和治疗,以防止发病和死亡。优化脑膜炎和脑炎的治疗可加快症状的缓解,降低神经元损伤的风险,并将潜在的长期神经系统后遗症降至最低。本文旨在全面概述脑膜炎和脑炎的病因和病理生理学,讨论诊断标准,并强调治疗的临床指征,包括当前的治疗策略和新出现的治疗方法。
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Encephalitis and Meningitis: Indications for Intervention.

Meningitis and encephalitis are characterized by inflammation of the meninges and brain parenchyma, respectively. The blood-brain barrier normally acts as a protective barrier against inflammation in the central nervous system (CNS), but its compromise requires prompt diagnosis and treatment to prevent morbidity and mortality. Optimizing therapy for meningitis and encephalitis can expedite resolution of symptoms, mitigating the risk of neuronal injury and minimizing potential long-term neurological sequelae. This paper aims to provide a comprehensive overview of the etiology and pathophysiology of meningitis and encephalitis, discussing the diagnostic criteria, and emphasizing the clinical indications for treatments, including current treatment strategies, and emerging therapeutic approaches.

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