肥厚性心肌病心肌肥厚的成像及其鉴别诊断。

IF 2 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Current Opinion in Cardiology Pub Date : 2023-09-01 DOI:10.1097/HCO.0000000000001070
Lana Rashdan, James Hodovan, Ahmad Masri
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引用次数: 0

摘要

回顾目的:本研究的目的是回顾肥厚性心肌病(HCM)心肌肥大的影像学表现及其表型。HCM中心肌肌球蛋白抑制剂的引入强调了仔细评估心肌肥厚潜在原因的必要性。最近发现:心肌肥大的影像学进展主要集中在提高准确性、诊断和预测预后。从改善心肌质量和功能的评估,到不使用钆评估心肌纤维化,成像仍然是了解心肌肥大及其下游影响的主要工具。我们注意到在区分运动员心脏和HCM方面的进展,并且由于对治疗方法的影响,使用无创方法对心脏淀粉样变性的诊断率越来越高。最后,分享了法布里病的最新数据以及与HCM区分其他表型的数据。摘要:HCM的肥大成像和排除其他表型是HCM患者护理的核心。这一领域将继续快速发展,因为疾病改善疗法正在研究中,并正在推进到临床。
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Imaging cardiac hypertrophy in hypertrophic cardiomyopathy and its differential diagnosis.

Purpose of review: The aim of this study was to review imaging of myocardial hypertrophy in hypertrophic cardiomyopathy (HCM) and its phenocopies. The introduction of cardiac myosin inhibitors in HCM has emphasized the need for careful evaluation of the underlying cause of myocardial hypertrophy.

Recent findings: Advances in imaging of myocardial hypertrophy have focused on improving precision, diagnosis, and predicting prognosis. From improved assessment of myocardial mass and function, to assessing myocardial fibrosis without the use of gadolinium, imaging continues to be the primary tool in understanding myocardial hypertrophy and its downstream effects. Advances in differentiating athlete's heart from HCM are noted, and the increasing rate of diagnosis in cardiac amyloidosis using noninvasive approaches is especially highlighted due to the implications on treatment approach. Finally, recent data on Fabry disease are shared as well as differentiating other phenocopies from HCM.

Summary: Imaging hypertrophy in HCM and ruling out other phenocopies is central to the care of patients with HCM. This space will continue to rapidly evolve, as disease-modifying therapies are under investigation and being advanced to the clinic.

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来源期刊
Current Opinion in Cardiology
Current Opinion in Cardiology 医学-心血管系统
CiteScore
4.20
自引率
4.30%
发文量
78
审稿时长
6-12 weeks
期刊介绍: ​​​​​​Current Opinion in Cardiology is a bimonthly publication offering a unique and wide ranging perspective on the key developments in the field. Each issue features hand-picked review articles from our team of expert editors. With fourteen disciplines published across the year – including arrhythmias, molecular genetics, HDL cholesterol and clinical trials – every issue also contains annotated reference detailing the merits of the most important papers.
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