Desmond Beall——加拿大人对横纹肌溶解的贡献。

IF 2.2 4区 医学 Q2 SURGERY Canadian Journal of Surgery Pub Date : 2023-07-01 DOI:10.1503/cjs.013722
Sarah MacVicar, Alexandra Hetherington, Matt Strickland
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引用次数: 0

摘要

作为生物化学研究多个领域的先驱,德斯蒙德·比尔对加拿大医学史做出了重要贡献。他的遗产为几项现代科学进步奠定了基础,从他在多伦多关于马雌激素的博士工作(导致了结合雌激素的发展)到第二次世界大战期间关于横纹肌溶解的里程碑式工作。虽然之前对创伤性横纹肌溶解的病理生理学有一些理论上的了解,Beall和他的同事Eric Bywaters发表了关于1940年闪电战轰炸期间治疗的病人的论文,大大推进了这一研究领域。战争结束后,比尔转向工业界工作,并能够将他的科学进步转化为影响全球患者生活的产品。本文取材于已出版的作品以及与家庭成员的个人交流,是对一位杰出但相对不为人知的科学家的纪念。
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Desmond Beall - a Canadian's contribution to understanding rhabdomyolysis.

A pioneer in multiple areas of biochemical research, Desmond Beall made important contributions to Canadian medical history. His legacy laid the foundation for several modern scientific advances, extending from his doctoral work in Toronto on equine estrogen (which led to the development of conjugated estrogens) to landmark work on rhabdomyolysis during World War II. Though some theoretical understanding of the pathophysiology of traumatic rhabdomyolysis existed previously, Beall and his colleague Eric Bywaters substantially advanced this field of study with their publications on patients treated during the 1940 Blitz bombings. After the war, Beall shifted to working in industry and was able to translate his scientific advances into products affecting the lives of patients worldwide. Drawing from published works and personal communications with family members, this article is a memorial to a remarkable yet relatively unknown scientist.

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来源期刊
CiteScore
3.00
自引率
8.00%
发文量
120
审稿时长
6-12 weeks
期刊介绍: The mission of CJS is to contribute to the meaningful continuing medical education of Canadian surgical specialists, and to provide surgeons with an effective vehicle for the dissemination of observations in the areas of clinical and basic science research.
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