乳酸菌发酵玉子渣提取物对大鼠肝细胞和附睾脂肪组织的抗肥胖作用

Q3 Immunology and Microbiology Applied Microscopy Pub Date : 2023-08-09 DOI:10.1186/s42649-023-00090-9

Han-Na Chu, Haeng-Ran Kim, Kyeong-A. Jang, Yu-Jin Hwang, Jeong-Sang Kim

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引用次数: 0

摘要

本研究以乳酸菌发酵的玉子果渣提取物为研究对象，观察其对高脂饮食性肥胖大鼠8周的抗肥胖作用。乳酸菌发酵鱼子渣提取物处理组与对照组相比，附睾脂肪细胞大小显著减小，约33%。电镜观察肝细胞微结构显示，肝细胞内脂滴数量较少，线粒体数量较多，嵴明显，粗面内质网发育良好，池池和核糖体堆积。由此可见，乳酸菌发酵的玉子渣提取物通过影响体重和脂质积累，具有防治肥胖的作用。

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Anti-obesity effects of yuja (Citrus junos Sieb ex Tanaka) pomace extract fermented with lactic acid bacteria on the hepatocytes and epididymal fat tissue of rats

This study investigated the anti-obesity effects of yuja pomace extract fermented with lactic acid bacteria in rats with high-fat diet-induced obesity over a period of eight weeks. Epididymal fat cell size was significantly smaller, by about 33%, in the treatment groups given yuja pomace extract fermented with lactic acid bacteria compared to the CON group. Electron microscopic observation of hepatocyte microstructure showed that the number of lipid droplets was lower in hepatocytes, the number of mitochondria was higher, along with distinct cristae, and the rough endoplasmic reticula were well developed with stacks of cisternae and ribosomes. Thus, it is believed that yuja pomace extract fermented with lactic acid bacteria, by influencing body weight and lipid accumulation, is effective in the prevention and treatment of obesity.

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来源期刊

Applied Microscopy Immunology and Microbiology-Applied Microbiology and Biotechnology

CiteScore

3.40

自引率

0.00%

发文量

审稿时长

10 weeks

期刊介绍： Applied Microscopy is a peer-reviewed journal sponsored by the Korean Society of Microscopy. The journal covers all the interdisciplinary fields of technological developments in new microscopy methods and instrumentation and their applications to biological or materials science for determining structure and chemistry. ISSN: 22875123, 22874445.