Targeting the synthetic lethal relationship between FOCAD and TUT7 represents a potential therapeutic opportunity for TUT4/7 small molecule inhibitors in cancer.

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DOI:10.1158/1535-7163.MCT-24-0176
作者：Robinson Triboulet,?Khikmet Sadykov,?Darren M Harvey,?David M Wilson,?Michael J Steinbaugh,?Christopher B Mayo,?Dillon Hawley,?Andrew Madanjian,?Corey Fyfe,?Christina Bracken,?Izarys Rivera-Rivera,?An
文献类型：期刊论文
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American Association for Cancer Research (AACR)

Abstract：Targeting synthetic lethal interactions between genes has emerged as a promising strategy for cancer therapy. This study explores the intricate interplay between terminal uridyltransferase 4

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